Dynamics and Determinants of Staphylococcus aureus Carriage in Infancy: the Generation R Study

Serial nasal swabs were collected at the ages of 1.5, 6, and 14 months from 443 infants in the Generation R Study. The objective was to study the dynamics and determinants of Staphylococcus aureus nasal carriage in the first year of life. The prevalence of S. aureus carriage decreased in the first y...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Clinical Microbiology 2008-10, Vol.46 (10), p.3517-3521
Main Authors: Lebon, Ankie, Labout, Joost A.M, Verbrugh, Henri A, Jaddoe, Vincent W.V, Hofman, Albert, van Wamel, Willem, Moll, Henriette A, van Belkum, Alex
Format: Article
Language:English
Subjects:
Age Factors
Bacteriology
Biological and medical sciences
Carrier State - epidemiology
Carrier State - microbiology
Epidemiology
Female
Fundamental and applied biological sciences. Psychology
Humans
Infant
Infant, Newborn
Male
Microbiology
Miscellaneous
Nose - microbiology
Prevalence
Staphylococcal Infections - epidemiology
Staphylococcal Infections - microbiology
Staphylococcus aureus - isolation & purification
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Serial nasal swabs were collected at the ages of 1.5, 6, and 14 months from 443 infants in the Generation R Study. The objective was to study the dynamics and determinants of Staphylococcus aureus nasal carriage in the first year of life. The prevalence of S. aureus carriage decreased in the first year of life, from 52.1% at the age of 1.5 months to 12.9% at 14 months. Persistent carriage, defined as continuous carriage of the same S. aureus strain at the three sampling moments, was rarely detected in early infancy.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.00641-08