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Herpes Simplex Virus 1 Serine/Threonine Kinase US3 Hyperphosphorylates IRF3 and Inhibits Beta Interferon Production
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Published in: | Journal of Virology 2013-12, Vol.87 (23), p.12814-12827 |
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container_end_page | 12827 |
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container_title | Journal of Virology |
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creator | Wang, Shuai Wang, Kezhen Lin, Rongtuan Zheng, Chunfu |
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</description><identifier>ISSN: 0022-538X</identifier><identifier>EISSN: 1098-5514</identifier><identifier>DOI: 10.1128/JVI.02355-13</identifier><identifier>PMID: 24049179</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Amino Acid Motifs ; Animals ; Down-Regulation ; Female ; Herpes Simplex - genetics ; Herpes Simplex - metabolism ; Herpes Simplex - virology ; Herpes simplex virus 1 ; Herpesvirus 1, Human - enzymology ; Herpesvirus 1, Human - genetics ; Humans ; Interferon Regulatory Factor-3 - chemistry ; Interferon Regulatory Factor-3 - genetics ; Interferon Regulatory Factor-3 - metabolism ; Interferon-beta - genetics ; Interferon-beta - metabolism ; Mice ; Mice, Inbred C57BL ; Phosphorylation ; Promoter Regions, Genetic ; Protein Binding ; Protein-Serine-Threonine Kinases - genetics ; Protein-Serine-Threonine Kinases - metabolism ; Sendai virus ; Viral Proteins - genetics ; Viral Proteins - metabolism ; Virus-Cell Interactions</subject><ispartof>Journal of Virology, 2013-12, Vol.87 (23), p.12814-12827</ispartof><rights>Copyright © 2013, American Society for Microbiology. All Rights Reserved. 2013 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c554t-e4d7a2ccbf6176c5082acc6da69b19dd72d1064de1480c6c2a419b04335127303</citedby><cites>FETCH-LOGICAL-c554t-e4d7a2ccbf6176c5082acc6da69b19dd72d1064de1480c6c2a419b04335127303</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838156/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838156/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,724,777,781,882,3175,3176,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24049179$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Shuai</creatorcontrib><creatorcontrib>Wang, Kezhen</creatorcontrib><creatorcontrib>Lin, Rongtuan</creatorcontrib><creatorcontrib>Zheng, Chunfu</creatorcontrib><title>Herpes Simplex Virus 1 Serine/Threonine Kinase US3 Hyperphosphorylates IRF3 and Inhibits Beta Interferon Production</title><title>Journal of Virology</title><addtitle>J Virol</addtitle><description>Article Usage Stats
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</description><subject>Amino Acid Motifs</subject><subject>Animals</subject><subject>Down-Regulation</subject><subject>Female</subject><subject>Herpes Simplex - genetics</subject><subject>Herpes Simplex - metabolism</subject><subject>Herpes Simplex - virology</subject><subject>Herpes simplex virus 1</subject><subject>Herpesvirus 1, Human - enzymology</subject><subject>Herpesvirus 1, Human - genetics</subject><subject>Humans</subject><subject>Interferon Regulatory Factor-3 - chemistry</subject><subject>Interferon Regulatory Factor-3 - genetics</subject><subject>Interferon Regulatory Factor-3 - metabolism</subject><subject>Interferon-beta - genetics</subject><subject>Interferon-beta - metabolism</subject><subject>Mice</subject><subject>Mice, Inbred C57BL</subject><subject>Phosphorylation</subject><subject>Promoter Regions, Genetic</subject><subject>Protein Binding</subject><subject>Protein-Serine-Threonine Kinases - genetics</subject><subject>Protein-Serine-Threonine Kinases - metabolism</subject><subject>Sendai virus</subject><subject>Viral Proteins - genetics</subject><subject>Viral Proteins - metabolism</subject><subject>Virus-Cell Interactions</subject><issn>0022-538X</issn><issn>1098-5514</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNqFkU1v1DAQhi0EokvhxhlZ4sKBtB5_JbkglYqyC5VAbFtxsxxntnGVjYOdFPbfY9hSwYnDaMaaZ1555iXkObAjAF4df7haHTEulCpAPCALYHVVKAXyIVkwxnmhRPX1gDxJ6YYxkFLLx-SASyZrKOsFSUuMIya69tuxxx_0ysc5UaBrjH7A44suYhhyRT_6wSakl2tBl7sxD3Uh5Yi73k55fvXlTFA7tHQ1dL7xU6JvcbL5NWHcYAwD_RxDO7vJh-EpebSxfcJnd_mQXJ69uzhdFuef3q9OT84Lp5ScCpRtablzzUZDqZ1iFbfO6dbquoG6bUveAtOyRZAVc9pxK6FumBRCAS8FE4fkzV53nJsttg6HKdrejNFvbdyZYL35tzP4zlyHWyMqUYHSWeDVnUAM32ZMk9n65LDv7YBhTga0lpzVOp__v6iUNa9YXcqMvt6jLoaUIm7ufwTM_LLUZEvNb0sNiIy_-HuLe_iPhxl4uQc6f9199xGNTVtzc-tNVRouTFYEKX4C9dCorg</recordid><startdate>20131201</startdate><enddate>20131201</enddate><creator>Wang, Shuai</creator><creator>Wang, Kezhen</creator><creator>Lin, Rongtuan</creator><creator>Zheng, Chunfu</creator><general>American Society for Microbiology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7T5</scope><scope>7U9</scope><scope>H94</scope><scope>5PM</scope></search><sort><creationdate>20131201</creationdate><title>Herpes Simplex Virus 1 Serine/Threonine Kinase US3 Hyperphosphorylates IRF3 and Inhibits Beta Interferon Production</title><author>Wang, Shuai ; Wang, Kezhen ; Lin, Rongtuan ; Zheng, Chunfu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c554t-e4d7a2ccbf6176c5082acc6da69b19dd72d1064de1480c6c2a419b04335127303</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Amino Acid Motifs</topic><topic>Animals</topic><topic>Down-Regulation</topic><topic>Female</topic><topic>Herpes Simplex - genetics</topic><topic>Herpes Simplex - metabolism</topic><topic>Herpes Simplex - virology</topic><topic>Herpes simplex virus 1</topic><topic>Herpesvirus 1, Human - enzymology</topic><topic>Herpesvirus 1, Human - genetics</topic><topic>Humans</topic><topic>Interferon Regulatory Factor-3 - chemistry</topic><topic>Interferon Regulatory Factor-3 - genetics</topic><topic>Interferon Regulatory Factor-3 - metabolism</topic><topic>Interferon-beta - genetics</topic><topic>Interferon-beta - metabolism</topic><topic>Mice</topic><topic>Mice, Inbred C57BL</topic><topic>Phosphorylation</topic><topic>Promoter Regions, Genetic</topic><topic>Protein Binding</topic><topic>Protein-Serine-Threonine Kinases - genetics</topic><topic>Protein-Serine-Threonine Kinases - metabolism</topic><topic>Sendai virus</topic><topic>Viral Proteins - genetics</topic><topic>Viral Proteins - metabolism</topic><topic>Virus-Cell Interactions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Shuai</creatorcontrib><creatorcontrib>Wang, Kezhen</creatorcontrib><creatorcontrib>Lin, Rongtuan</creatorcontrib><creatorcontrib>Zheng, Chunfu</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of Virology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Shuai</au><au>Wang, Kezhen</au><au>Lin, Rongtuan</au><au>Zheng, Chunfu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Herpes Simplex Virus 1 Serine/Threonine Kinase US3 Hyperphosphorylates IRF3 and Inhibits Beta Interferon Production</atitle><jtitle>Journal of Virology</jtitle><addtitle>J Virol</addtitle><date>2013-12-01</date><risdate>2013</risdate><volume>87</volume><issue>23</issue><spage>12814</spage><epage>12827</epage><pages>12814-12827</pages><issn>0022-538X</issn><eissn>1098-5514</eissn><abstract>Article Usage Stats
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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>24049179</pmid><doi>10.1128/JVI.02355-13</doi><tpages>14</tpages><oa>free_for_read</oa></addata></record> |
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source | American Society for Microbiology Journals; PubMed Central |
subjects | Amino Acid Motifs Animals Down-Regulation Female Herpes Simplex - genetics Herpes Simplex - metabolism Herpes Simplex - virology Herpes simplex virus 1 Herpesvirus 1, Human - enzymology Herpesvirus 1, Human - genetics Humans Interferon Regulatory Factor-3 - chemistry Interferon Regulatory Factor-3 - genetics Interferon Regulatory Factor-3 - metabolism Interferon-beta - genetics Interferon-beta - metabolism Mice Mice, Inbred C57BL Phosphorylation Promoter Regions, Genetic Protein Binding Protein-Serine-Threonine Kinases - genetics Protein-Serine-Threonine Kinases - metabolism Sendai virus Viral Proteins - genetics Viral Proteins - metabolism Virus-Cell Interactions |
title | Herpes Simplex Virus 1 Serine/Threonine Kinase US3 Hyperphosphorylates IRF3 and Inhibits Beta Interferon Production |
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