Association of Active Caspase 8 with the Mitochondrial Membrane during Apoptosis: Potential Roles in Cleaving BAP31 and Caspase 3 and Mediating Mitochondrion-Endoplasmic Reticulum Cross Talk in Etoposide-Induced Cell Death

• Published in: Molecular and Cellular Biology 2004-08, Vol.24 (15), p.6592-6607
• Main Authors: Chandra, Dhyan, Choy, Grace, Deng, Xiaodi, Bhatia, Bobby, Daniel, Peter, Tang, Dean G.
• Format: Article
• Language: English
• Subjects: Antineoplastic Agents, Phytogenic - pharmacology; Apoptosis; Blotting, Western; Calcium - metabolism; Caspase 3; Caspase 8; Caspases - metabolism; Cell Death; Cell Growth and Development; Cell Line; Cell Line, Tumor; Cell Membrane - metabolism; Cell-Free System; Centrifugation, Density Gradient; Dose-Response Relationship, Drug; Down-Regulation; Endopeptidase K - metabolism; Endoplasmic Reticulum - metabolism; Enzyme Activation; Etoposide - pharmacology; Humans; Jurkat Cells; Membrane Proteins - metabolism; Microscopy, Fluorescence; Mitochondria - metabolism; Models, Biological; Protein Binding; Protein Structure, Tertiary; RNA, Small Interfering - metabolism; Salts - pharmacology; Subcellular Fractions - metabolism; Sucrose - pharmacology; Transfection
• ISSN: 0270-7306; 1098-5549; 1098-5549
• DOI: 10.1128/MCB.24.15.6592-6607.2004

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