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Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements
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Published in: | Molecular and Cellular Biology 2013-05, Vol.33 (9), p.1711-1722 |
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container_title | Molecular and Cellular Biology |
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creator | Ramamoorthy, Sivapriya Cidlowski, John A. |
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doi_str_mv | 10.1128/MCB.01151-12 |
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</description><identifier>ISSN: 0270-7306</identifier><identifier>ISSN: 1098-5549</identifier><identifier>EISSN: 1098-5549</identifier><identifier>DOI: 10.1128/MCB.01151-12</identifier><identifier>PMID: 23428870</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Animals ; Cell Line ; Chromatin - metabolism ; Down-Regulation - drug effects ; Drug Resistance ; Exons - drug effects ; Glucocorticoids - pharmacology ; Histone Deacetylases - metabolism ; Humans ; Ligands ; Male ; Mice ; Mice, Inbred C57BL ; Nuclear Receptor Co-Repressor 1 - metabolism ; Rats ; Receptors, Glucocorticoid - genetics ; Receptors, Glucocorticoid - metabolism ; Response Elements - drug effects ; Transcriptional Activation - drug effects</subject><ispartof>Molecular and Cellular Biology, 2013-05, Vol.33 (9), p.1711-1722</ispartof><rights>Copyright © 2013, American Society for Microbiology 2013</rights><rights>Copyright © 2013, American Society for Microbiology. All Rights Reserved. 2013 American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c483t-7ca3764d6be9832d15060df348ddbc76ef69cc1629d2f0a1fd75945866dd34b53</citedby><cites>FETCH-LOGICAL-c483t-7ca3764d6be9832d15060df348ddbc76ef69cc1629d2f0a1fd75945866dd34b53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624172/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624172/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23428870$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ramamoorthy, Sivapriya</creatorcontrib><creatorcontrib>Cidlowski, John A.</creatorcontrib><title>Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements</title><title>Molecular and Cellular Biology</title><addtitle>Mol Cell Biol</addtitle><description>Article Usage Stats
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</description><subject>Animals</subject><subject>Cell Line</subject><subject>Chromatin - metabolism</subject><subject>Down-Regulation - drug effects</subject><subject>Drug Resistance</subject><subject>Exons - drug effects</subject><subject>Glucocorticoids - pharmacology</subject><subject>Histone Deacetylases - metabolism</subject><subject>Humans</subject><subject>Ligands</subject><subject>Male</subject><subject>Mice</subject><subject>Mice, Inbred C57BL</subject><subject>Nuclear Receptor Co-Repressor 1 - metabolism</subject><subject>Rats</subject><subject>Receptors, Glucocorticoid - genetics</subject><subject>Receptors, Glucocorticoid - metabolism</subject><subject>Response Elements - drug effects</subject><subject>Transcriptional Activation - drug effects</subject><issn>0270-7306</issn><issn>1098-5549</issn><issn>1098-5549</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><recordid>eNp1kUGP1CAYhhujccfVm2eDd7tCaaG9mLjN7jjJrCYTPRMKX1tMCw0wjvMD_V-2VjdrjCcSeN6HD94keUnwFSFZ-fauvr7ChBQkJdmjZENwVaZFkVePkw3OOE45xewieRbCV4wxqzB9mlxkNM_KkuNN8mNvOml1urP6qECjA0weQjDOItei2APaDkfllPPRKGcWQMEUnUdbsIB2Ad2BNjLO0eaMpEUfa3cgDzW1G6cBvqNb58eV2jvbpQdpO0B1790oo7FoZyN4qeIcCehkYr_seNmBNerfGcI0Y4BuBhjBxvA8edLKIcCL3-tl8uX25nP9Id1_2u7q9_tU5SWNKVeScpZr1kBV0kyTAjOsW5qXWjeKM2hZpRRhWaWzFkvSal5UeVEypjXNm4JeJu9W73Rs5scoWEYcxOTNKP1ZOGnE3yfW9KJz3wRlWU54NgverALlXQge2vsswWKpU8x1il91CrLgrx7edw__6W8G-AoY287_K0_OD1pEeR6cb720ygRB_6N-vSZ70_Un40HIMIpRNYJSUQnCCaE_AaYivc4</recordid><startdate>20130501</startdate><enddate>20130501</enddate><creator>Ramamoorthy, Sivapriya</creator><creator>Cidlowski, John A.</creator><general>American Society for Microbiology</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20130501</creationdate><title>Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements</title><author>Ramamoorthy, Sivapriya ; Cidlowski, John A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c483t-7ca3764d6be9832d15060df348ddbc76ef69cc1629d2f0a1fd75945866dd34b53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Animals</topic><topic>Cell Line</topic><topic>Chromatin - metabolism</topic><topic>Down-Regulation - drug effects</topic><topic>Drug Resistance</topic><topic>Exons - drug effects</topic><topic>Glucocorticoids - pharmacology</topic><topic>Histone Deacetylases - metabolism</topic><topic>Humans</topic><topic>Ligands</topic><topic>Male</topic><topic>Mice</topic><topic>Mice, Inbred C57BL</topic><topic>Nuclear Receptor Co-Repressor 1 - metabolism</topic><topic>Rats</topic><topic>Receptors, Glucocorticoid - genetics</topic><topic>Receptors, Glucocorticoid - metabolism</topic><topic>Response Elements - drug effects</topic><topic>Transcriptional Activation - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ramamoorthy, Sivapriya</creatorcontrib><creatorcontrib>Cidlowski, John A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Molecular and Cellular Biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ramamoorthy, Sivapriya</au><au>Cidlowski, John A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements</atitle><jtitle>Molecular and Cellular Biology</jtitle><addtitle>Mol Cell Biol</addtitle><date>2013-05-01</date><risdate>2013</risdate><volume>33</volume><issue>9</issue><spage>1711</spage><epage>1722</epage><pages>1711-1722</pages><issn>0270-7306</issn><issn>1098-5549</issn><eissn>1098-5549</eissn><abstract>Article Usage Stats
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ispartof | Molecular and Cellular Biology, 2013-05, Vol.33 (9), p.1711-1722 |
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source | PubMed Central |
subjects | Animals Cell Line Chromatin - metabolism Down-Regulation - drug effects Drug Resistance Exons - drug effects Glucocorticoids - pharmacology Histone Deacetylases - metabolism Humans Ligands Male Mice Mice, Inbred C57BL Nuclear Receptor Co-Repressor 1 - metabolism Rats Receptors, Glucocorticoid - genetics Receptors, Glucocorticoid - metabolism Response Elements - drug effects Transcriptional Activation - drug effects |
title | Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements |
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