Cardiac parasympathetic regulation: respective associations with cardiorespiratory fitness and training load

• Published in: American journal of physiology. Heart and circulatory physiology 2006-07, Vol.291 (1), p.H451-H458
• Main Authors: Buchheit, Martin, Gindre, Cyrille
• Format: Article
• Language: English
• Subjects: Adaptation, Physiological - physiology; Adult; Exercise - physiology; Feedback - physiology; Heart - innervation; Heart - physiology; Heart Rate - physiology; Humans; Life Sciences; Male; Neurons and Cognition; Parasympathetic Nervous System - physiology; Physical Exertion - physiology; Physical Fitness - physiology; Psychology and behavior; Vagus Nerve - physiology
• ISSN: 0363-6135; 1522-1539
• DOI: 10.1152/ajpheart.00008.2006

1 Laboratoire des Régulations Physiologiques et des Rythmes Biologiques chez l'Homme, Strasbourg; 2 Institut de Médecine du Sport de Troyes, Troyes; and 3 Laboratoire Mathématiques Appliquées aux Systèmes-Pôle Santé et Biotechnologies, École Centrale de Paris, Châtenay Malabry, France Submitted 3 January 2006 ; accepted in final form 22 February 2006 The objective of this study was to establish the separate associations between parasympathetic modulations of the heart [evaluated through heart rate (HR) variability (HRV) indexes and postexercise HR recovery (HRR) indexes] with cardiorespiratory fitness and training load. We have measured cardiorespiratory fitness through peak oxygen consumption ( O 2 max ) and estimated weekly training load with the Baecke sport score in 55 middle-aged individuals (30.8 ± 1.8 yr, body mass index 24.5 ± 0.4 kg/m 2 ). HRV indexes were analyzed at rest under controlled breathing, and HRR was estimated from HR curve fitting after maximal exercise or from measurements of the number of beats recovered at 60 s after exercise. Multiple linear regressions were used to investigate the separate relationships between vagal-related HRV indexes and O 2 max and Baecke scores. On the basis of their O 2 max and Baecke scores, subjects were classified as fit or unfit and as low trained (LT) or moderately trained (MT), which yielded four groups: Unfit LT , Unfit MT , Fit LT , and Fit MT . Vagal-related HRV indexes were positively correlated with O 2 max ( P < 0.05) but not with Baecke scores. In contrast, HRR indexes were related to Baecke scores ( P < 0.05) but not with O 2 max . Fit LT and Fit MT had significantly higher ( P < 0.05) normalized vagal-related HRV indexes than Unfit LT and Unfit MT , but HRR did not change. Moderate training was associated with significantly lower HRR indexes both in Unfit MT and Fit MT compared with Unfit LT and Fit LT , but there was no difference in vagal-related HRV indexes. These results indicate that vagal-related HRV indexes are related more to cardiorespiratory fitness, whereas HRR appears to be better associated with training load. vagal-related indexes; postexercise heart rate recovery; aerobic training Address for reprint requests and other correspondence: M. Buchheit, Laboratoire des Régulations Physiologiques et des Rythmes Biologiques chez l'Homme, Faculté de Médecine, 4, rue Kirschleger, 67085 Strasbourg Cedex, France (e-mail: martin.buchheit{at}physio-ulp.u-strasbg.fr )