RuCl3 · nH2O as Catalyst for Diastereoselective Direct Aldol Reaction : An Efficient Route to Hormone Steroid Derivatives

RuIII-catalyzed regio- and diastereoselective direct aldol reaction of progesterone with aromatic aldehydes has been developed in good yields (58–78%). Advantages of this method include catalytic efficiency, short reaction times, and ease of operation and workup.

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Bibliographic Details
Published in:Organic chemistry International 2010, Vol.2011 (2011), p.1-5
Main Authors: Tabatabaeian, Khalil, Keshavarz, Elahe, Mamaghani, Manouchehr, Mahmoodi, Nosrat O.
Format: Article
Language:English
Online Access:Get full text
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Summary:RuIII-catalyzed regio- and diastereoselective direct aldol reaction of progesterone with aromatic aldehydes has been developed in good yields (58–78%). Advantages of this method include catalytic efficiency, short reaction times, and ease of operation and workup.
ISSN:2090-200X
2090-2018
DOI:10.1155/2011/325291