Successful Orthotopic Liver Transplant for Diffuse Biliary Papillomatosis With Malignant Transformation: A Case Report With Long-Term Follow-Up

In patients with biliary papillomatosis, complete resection of the biliary tree (that is, liver transplant along with duodenocephalo-pancreatectomy) is considered the only potential curative treatment, given its diffuse pattern and likelihood of malignant transformation. Nevertheless, such a combine...

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Bibliographic Details
Published in:Experimental and clinical transplantation 2019-12, Vol.17 (6), p.835-837
Main Authors: Ferraro, Daniele, Levi Sandri, Giovanni Battista, Vennarecci, Giovanni, Santoro, Roberto, Colasanti, Marco, Meniconi, Roberto L., Lepiane, Pasquale, Ettorre, Giuseppe M.
Format: Article
Language:English
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Summary:In patients with biliary papillomatosis, complete resection of the biliary tree (that is, liver transplant along with duodenocephalo-pancreatectomy) is considered the only potential curative treatment, given its diffuse pattern and likelihood of malignant transformation. Nevertheless, such a combined surgical approach can increase patient morbidity and mortality and should be considered only when the distal part of the common bile duct is involved. Here, we avoided duodenocephalo-pancreatectomy in a patient with distal common bile duct free from disease; this approach did not negatively influence survival and appeared to be safer during liver transplant.
ISSN:1304-0855
2146-8427
DOI:10.6002/ect.2017.0134