Administering RiaSTAP for Congenital Afibrinogenemia During Liver Transplant

Liver transplant has occasionally been performed in the presence of congenital afibrinogenemia and has been rarely used to treat it. Historically, to safely manage coagulopathy during transplant, these patients have been administered a combination of fresh frozen plasma and cryoprecipitate. In this...

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Bibliographic Details
Published in:Experimental and clinical transplantation 2021-03, Vol.19 (3), p.269-272
Main Authors: Giordano, Chris, Johnson, Chris, Lawson, Janice, Rajasekhar, Anita, Thomas, Elizabeth
Format: Article
Language:English
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Tıp
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Summary:Liver transplant has occasionally been performed in the presence of congenital afibrinogenemia and has been rarely used to treat it. Historically, to safely manage coagulopathy during transplant, these patients have been administered a combination of fresh frozen plasma and cryoprecipitate. In this case report, we discuss the first reported use of recombinant fibrinogen to treat such a patient and the decision-making process considered to balance the thrombotic and hemorrhagic risks.
ISSN:1304-0855
2146-8427
DOI:10.6002/ect.2017.0316