Contemporary management of renal transplant recipients with de novo urolithiasis: A single ınstitution experience and review of the literature

Objectives: We report on the long-term follow-up of managing allograft stones at a single tertiary referral institution and review the relevant literature. Materials and Methods: A retrospective analysis of renal allograft recipient charts was performed to identify patients who developed allograft l...

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Published in:Experimental and clinical transplantation 2017-06, Vol.15 (3), p.277-281
Main Authors: Harraz,Ahmed M, Zahran,Mohamed H, Kamal,Ahmed I, El-Hefnawy,Ahmed S, Osman,Yasser, Soliman,Shady A, Kamal,Mohamed M, Ali-El-Dein,Beder, Shokeir,Ahmed A
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Language:English
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Summary:Objectives: We report on the long-term follow-up of managing allograft stones at a single tertiary referral institution and review the relevant literature. Materials and Methods: A retrospective analysis of renal allograft recipient charts was performed to identify patients who developed allograft lithiasis between 1974 and 2009. Patient and stone characteristics, diagnoses, treatments, and outcomes were described. Results: Sixteen patients developed 22 stones after a median follow-up of 170 months (range, 51-351 mo). The mean (standard deviation) and median diameter of the stones were 13.8 (8.5) mm and 11 mm. Among these, 3 stones were treated conservatively, 3 by shock-wave lithotripsy, and 7 by cystolitholapaxy. Seven patients underwent percutaneous treatment in the form of percutaneous nephrostomy tube fixation and spontaneous passage of stone (1 stone), shock-wave lithotripsy (1 stone), antegrade stenting (1 stone), and percutaneous nephrolithotomy (6 stones). All patients were stone free after treatment, except for 2 patients whose stones were stable and peripheral on long-term follow-up. Conclusions: Allograft lithiasis requires a multimodal treatment tailored according to stone and graft characteristics. Protocols regarding spontaneous passage can be adopted if there is no harm to the graft and the patient is compliant. Careful attention to the anatomy during percutaneous nephrostomy tube placement is mandatory to avoid intestinal loop injury. A more attentive follow-up is required for early stone management.
ISSN:1304-0855
2146-8427
DOI:10.6002/ect.2016.0094