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Liver biopsy results in potential donor evaluation in living related liver transplant
Objectives: The number of living-donor liver transplants has been increasing due to the growing discrepancy between the number of patients on wait lists for liver transplant and the availability of deceased donations. Evaluations of potential liver donors should ensure the safety of the surgical pro...
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Published in: | Experimental and clinical transplantation 2018-03, Vol.16 (1), p.35-37 |
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Main Authors: | , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | Get full text |
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Summary: | Objectives: The number of living-donor liver
transplants has been increasing due to the growing
discrepancy between the number of patients on wait
lists for liver transplant and the availability of
deceased donations. Evaluations of potential liver
donors should ensure the safety of the surgical
procedure for both the donor and recipient. Liver
biopsy is the criterion standard for selecting optimal
donors. In this study, we evaluated the importance of
preoperative liver biopsy in selecting donor candidates.
Materials and Methods: We evaluated the data of 612
living-related liver donor candidates who received
liver biopsies between January 2001 and June 2017 at
our center.
Results: In the 612 liver donor candidates (328 male,
284 female; age range, 18-69 years), 416 liver biopsies
(68%) were reported as normal and 196 liver biopsies
(32%) had pathologic findings. Of 196 donors with
pathologic findings, 86 (44%) had fatty changes and
24 (12%) had portal inflammation.
Conclusions: The high rate of pathologic findings in
liver biopsy of healthy-appearing donor candidates
indicated the importance of liver biopsy in the
preoperative evaluation of donors. |
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ISSN: | 1304-0855 2146-8427 |
DOI: | 10.6002/ect.TOND-TDTD2017.O5 |