In vivo investigation of DMSA-coated magnetic fluid

Summary form only given. Magnetic fluids (MFs) have been used as a promising technological basis for biomedical applications. In the present study a biocompatible magnetic fluid (BMF) sample is given as an intravenous bolus dose to mice. Magnetic resonance (MR) and light microscopy (LM) are used to...

Full description

Saved in:
Bibliographic Details
Main Authors: Lacava, Z.G.M., Chaves, S.B., Lacava, L.M., Morais, P.C., Garcia, V.A.P., Silva, O., Pelegrini, F., Buske, N., Gansau, C., Curi, R., Azevedo, R.B.
Format: Conference Proceeding
Language:English
Subjects:
Biological materials
Biomedical materials
In vivo
Magnetic force microscopy
Magnetic liquids
Magnetic materials
Magnetic resonance
Mice
Nanoparticles
Nanostructured materials
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary form only given. Magnetic fluids (MFs) have been used as a promising technological basis for biomedical applications. In the present study a biocompatible magnetic fluid (BMF) sample is given as an intravenous bolus dose to mice. Magnetic resonance (MR) and light microscopy (LM) are used to investigate the biodistribution of the nanomagnetic-based material over several organs and the time-decay of the BMF sample in the blood circulation, up to four hours after injection. The BMF sample used in this study contains magnetite nanoparticles surface-coated with DMSA to obtain a stable sample at physiological pH and salinity.
DOI:10.1109/INTMAG.2002.1000988