A mm-sized implantable glucose sensor using a fluorescent hydrogel

This work proposes a millimeter-sized implantable glucose sensor using a fluorescent hydrogel based on boronic acids. The readout system is configured to provide an efficient wireless power transfer to the implantable sensor at 920-MHz frequency. The 675×959-µm 2 die fabricated in 180-nm CMOS consis...

Full description

Saved in:
Bibliographic Details
Main Authors: Lee, Hyeonkeon, Park, Honghyeon, Kim, Taein, Nam, Mi Song, Heo, Yun Jung, Kim, Sanghoek
Format: Conference Proceeding
Language:English
Subjects:
backscattered modulation
Capacitors
Fluorescence
fluorescence hydrogel
Glucose sensors
Hydrogels
implantable glucose sensor
load-shift keying
Wireless communication
Wireless power transfer
Wireless sensor networks
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This work proposes a millimeter-sized implantable glucose sensor using a fluorescent hydrogel based on boronic acids. The readout system is configured to provide an efficient wireless power transfer to the implantable sensor at 920-MHz frequency. The 675×959-µm 2 die fabricated in 180-nm CMOS consists of a rectifier, a bandgap reference, two regulators, a trans-impedance amplifier, two voltage-controlled ring oscillators, and a digital control with the total power consumption of 150 µW. The die is assembled with a 2.2 × 2.5-mm 2 antenna on PCB, an off-chip decoupling capacitor, an LED, and a photodiode. When the implantable sensor is surrounded by the fluorescent hydrogel and powered by the reader, the frequency of backscattered signals is encoded with the light intensity of the fluorescent glucose sensor, informing the glucose concentration. The miniaturization of the sensor minimizes the invasiveness, the potential discomfort, and immunity reaction against sensor, making it suitable for a long-term use after the implantation.
ISSN:2375-0995
DOI:10.1109/RFIC54547.2023.10186146