High spatial resolution, focused electrical stimulation of electrically-excitable tissue

A theoretical method is presented which uses wave-guiding principles to construct a focused point of stimulation at any location within a region of electrically-excitable tissue. The excitation is formed through the constructive interference of different frequency wave energies, traveling at frequen...

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Bibliographic Details
Main Authors: Laflen, J.B., Talavage, T.M., Sarychev, A.K.
Format: Conference Proceeding
Language:English
Subjects:
Acoustic propagation
Biomedical engineering
Cutoff frequency
Electrical stimulation
Electromagnetic propagation
Electromagnetic waveguides
Geometry
Interference
Pulse modulation
Spatial resolution
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Description
Summary:A theoretical method is presented which uses wave-guiding principles to construct a focused point of stimulation at any location within a region of electrically-excitable tissue. The excitation is formed through the constructive interference of different frequency wave energies, traveling at frequency-dependent velocities, which coalesce at the stimulation point. Further energy is brought to the stimulation point through reflection(s) at the boundaries of the wave-guiding structure. The resulting excitation signal depends upon several factors, including pulse envelope and duration, allowable frequency range, and stimulation time. A necessary trade-off exists amongst stimulation time, pulse duration, and the degree of focus.
ISSN:1094-687X
1558-4615
DOI:10.1109/IEMBS.2002.1053177