High spatial resolution, focused electrical stimulation of electrically-excitable tissue

A theoretical method is presented which uses wave-guiding principles to construct a focused point of stimulation at any location within a region of electrically-excitable tissue. The excitation is formed through the constructive interference of different frequency wave energies, traveling at frequen...

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Main Authors: Laflen, J.B., Talavage, T.M., Sarychev, A.K.
Format: Conference Proceeding
Language:English
Subjects:
Acoustic propagation
Biomedical engineering
Cutoff frequency
Electrical stimulation
Electromagnetic propagation
Electromagnetic waveguides
Geometry
Interference
Pulse modulation
Spatial resolution
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creator Laflen, J.B.
Talavage, T.M.
Sarychev, A.K.
description A theoretical method is presented which uses wave-guiding principles to construct a focused point of stimulation at any location within a region of electrically-excitable tissue. The excitation is formed through the constructive interference of different frequency wave energies, traveling at frequency-dependent velocities, which coalesce at the stimulation point. Further energy is brought to the stimulation point through reflection(s) at the boundaries of the wave-guiding structure. The resulting excitation signal depends upon several factors, including pulse envelope and duration, allowable frequency range, and stimulation time. A necessary trade-off exists amongst stimulation time, pulse duration, and the degree of focus.
doi_str_mv 10.1109/IEMBS.2002.1053177
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identifier ISSN: 1094-687X
ispartof Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology, 2002, Vol.3, p.2080-2081 vol.3
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source IEEE Electronic Library (IEL) Conference Proceedings
subjects Acoustic propagation
Biomedical engineering
Cutoff frequency
Electrical stimulation
Electromagnetic propagation
Electromagnetic waveguides
Geometry
Interference
Pulse modulation
Spatial resolution
title High spatial resolution, focused electrical stimulation of electrically-excitable tissue
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