Wide-band diffuse reflectance spectroscopy with a self-calibrating fiber-optic probe

We report on creation of a diffuse optical spectroscopy (DOS) setup in a wide VIS-NIR spectral range with a contact fiber-optic probe using a self-calibration technique. A four measurement procedure employing two source and two collection fibers arranged symmetrically allows to calculate extinction...

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Bibliographic Details
Main Authors: Turchin, I.V., Perekatova, V.V., Kostyuk, A.B., Orlova, A.G., Khilov, A.V., Sergeeva, E.A., Kirillin, M.Yu
Format: Conference Proceeding
Language:English
Subjects:
diffuse optical spectroscopy
In vivo
Integrated optics
Laser modes
light transport models
Measurement by laser beam
Nonhomogeneous media
Optical fibers
Physiology
self-calibration technique
tissue chromophores
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Summary:We report on creation of a diffuse optical spectroscopy (DOS) setup in a wide VIS-NIR spectral range with a contact fiber-optic probe using a self-calibration technique. A four measurement procedure employing two source and two collection fibers arranged symmetrically allows to calculate extinction spectrum of investigated tissue, excluding DOS instrumental characteristics and reducing the influence of absorption inhomogeneities on a tissue surface. High accuracy of a measured extinction spectra allows one to account for more tissue chromophores and precisely assess tissue physiological properties. The proposed system was applied successfully in preliminary in vivo studies.
ISSN:2642-5580
DOI:10.1109/ICLO59702.2024.10624081