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PET tracers surgical radio-guidance with using a small Compton-angles collimation probe

While effective detection of beta emitters could help localise positron emission tomography (PET) tracer-labelled tumours during surgery, current commercially available heavy and cumbersome surgical probes have imprecise directional capabilities and low { }^{18} \mathrm{~F} beta sensitivity, which o...

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Bibliographic Details
Main Authors: Mehadji, B., Dupont, M., Montrot, A., Roncali, E., Morel, C., Farman, B.
Format: Conference Proceeding
Language:English
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Summary:While effective detection of beta emitters could help localise positron emission tomography (PET) tracer-labelled tumours during surgery, current commercially available heavy and cumbersome surgical probes have imprecise directional capabilities and low { }^{18} \mathrm{~F} beta sensitivity, which overall lack relevance for clinical use. In this work, we explored an innovative approach based on small Compton-angles collimation. With 5 times greater directionality, comparable sensitivity and a significantly smaller probe diameter than basic mechanical collimation, small Compton-angles collimation can enable minimally invasive procedures to improve tumor detection during surgery.
ISSN:2577-0829
DOI:10.1109/NSS/MIC/RTSD57108.2024.10655950