High-Resolution Ultrasound Elastography of Articular Cartilage in Vitro

Articular cartilage is comprised of three histologic zones that exhibit different Young’s moduli. In addition, with age and disease the moduli can be altered. Therefore, diagnosis of joint diseases can be accomplished by detecting biomechanical properties of articular cartilage. In this report we in...

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Bibliographic Details
Published in:2006 International Conference of the IEEE Engineering in Medicine and Biology Society 2006, Vol.Supplement, p.6644-6647
Main Authors: Ginat, Daniel T., Hung, Gilberto, Gardner, Thomas R., Konofagou, Elisa E.
Format: Article
Language:English
Subjects:
Arthroscopy
Articular cartilage
Bovine
Capacitive sensors
Diseases
Elastography
Head
In vitro
Orthopedic surgery
Strain
Strain measurement
Ultrasonic imaging
Ultrasonic variables measurement
Ultrasound
USA Councils
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Summary:Articular cartilage is comprised of three histologic zones that exhibit different Young’s moduli. In addition, with age and disease the moduli can be altered. Therefore, diagnosis of joint diseases can be accomplished by detecting biomechanical properties of articular cartilage. In this report we investigate the feasibility of ultrasound elastography of bovine articular cartilage (n=5) employing instantaneous static compression using highresolution (55MHz) ultrasound elastography in vitro as a potential arthroscopic technique. Elastograms were computed using crosscorrelation technique and a gradient operator. The elastograms revealed near-zero strains within the samples, except at the articular surface and the interface between zones 1 and 2. The boundary conditions associated with the loading technique implemented herein that have to allow for a large acoustic window during imaging represent a fundamental challenge toward imparting local strains to the articular cartilage. Despite the complex boundary conditions, the feasibility of imaging strain within the cartilage during a sustained compression using elastographic techniques was demonstrated.
ISSN:1557-170X
DOI:10.1109/IEMBS.2006.260910