PCB/Polymer based micro-fluidic system for NMR Spectroscopy for nanoliters sample volume

In this work, we report on the realization of an innovating micro system for NMR spectroscopy on small sample volume (30-100 nL). We propose a micro system based on Printed Circuit Board (PCB) technology for the NMR probe associated to a micro fluidic system made with polymer (COC). The comparison o...

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Bibliographic Details
Main Authors: Pasquet, G., Chateaux, J.-F., Deman, A.-L., Morin, P., Fenet, B.
Format: Conference Proceeding
Language:English
Subjects:
Chemicals
Coils
Fabrication
Fluidic microsystems
Microfluidics
Nuclear magnetic resonance
Polymers
Printed circuits
Signal to noise ratio
Spectroscopy
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Summary:In this work, we report on the realization of an innovating micro system for NMR spectroscopy on small sample volume (30-100 nL). We propose a micro system based on Printed Circuit Board (PCB) technology for the NMR probe associated to a micro fluidic system made with polymer (COC). The comparison of several samples during the same NMR experiments could provide more precise information. In that context, we have realized a micro-fluidic system with two cavities, each cavity presenting a volume of 37 nl. The fabrication process is described, and first results are reported. The tight sealing of the micro-fluidic system has been demonstrated and preliminary NMR experiment results are presented.
ISSN:1094-687X
1558-4615
DOI:10.1109/IEMBS.2007.4352952