Loading…

Microarray Simulator as Educational Tool

As many real-world applications, microarray measurements are inapplicable for large-scale teaching purposes due to their laborious preparation process and expense. Fortunately, many phases of the array preparation process can be efficiently demonstrated by using a software simulator tool. Here we pr...

Full description

Saved in:
Bibliographic Details
Main Authors: Ruusuvuori, P., Nykter, M., Makiraatikka, E., Lehmussola, A., Korpelainen, T., Erkkila, T., Yli-Harja, O.
Format: Conference Proceeding
Language:English
Subjects:
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page 5922
container_issue
container_start_page 5919
container_title
container_volume
creator Ruusuvuori, P.
Nykter, M.
Makiraatikka, E.
Lehmussola, A.
Korpelainen, T.
Erkkila, T.
Yli-Harja, O.
description As many real-world applications, microarray measurements are inapplicable for large-scale teaching purposes due to their laborious preparation process and expense. Fortunately, many phases of the array preparation process can be efficiently demonstrated by using a software simulator tool. Here we propose the use of microarray simulator as an aiding tool in teaching of computational biology. Three case studies on educational use of the simulator are presented, which demonstrate the effect of gene knock-out, synthetic time series, and effect of noise sources. We conclude that the simulator, used for teaching the principles of microarray measurement technology, proved to be a useful tool in education.
doi_str_mv 10.1109/IEMBS.2007.4353695
format conference_proceeding
fullrecord <record><control><sourceid>ieee_6IE</sourceid><recordid>TN_cdi_ieee_primary_4353695</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ieee_id>4353695</ieee_id><sourcerecordid>4353695</sourcerecordid><originalsourceid>FETCH-LOGICAL-i338t-2fe5854736961e506fdf82fe01ac867500b7de8253c409ec25704f3cd717250b3</originalsourceid><addsrcrecordid>eNpVkEtPwzAQhM1LtCr5A3DJkUvC-rH2-ghVgEqtOLRI3Co3cSSjlCAnPfTf1xK9MJfRzieNVsPYPYeSc7BPi2r1si4FgCmVRKktXrDMGuJKKAWGCC7ZlCNSoTTHq3_MyOvEwKpCk_masGwYviFJ2oTplk04pUNqPmWPq1DH3sXojvk67A-dG_uYuyGvmkPtxtD_uC7f9H13x25a1w0-O_uMfb5Wm_l7sfx4W8yfl0WQksZCtB4JlUkPa-4RdNu0lELgriZtEGBnGk8CZa3A-lqgAdXKujHcCISdnLGHv97gvd_-xrB38bg9TyBPwoNHMA</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>conference_proceeding</recordtype></control><display><type>conference_proceeding</type><title>Microarray Simulator as Educational Tool</title><source>IEEE Electronic Library (IEL) Conference Proceedings</source><creator>Ruusuvuori, P. ; Nykter, M. ; Makiraatikka, E. ; Lehmussola, A. ; Korpelainen, T. ; Erkkila, T. ; Yli-Harja, O.</creator><creatorcontrib>Ruusuvuori, P. ; Nykter, M. ; Makiraatikka, E. ; Lehmussola, A. ; Korpelainen, T. ; Erkkila, T. ; Yli-Harja, O.</creatorcontrib><description>As many real-world applications, microarray measurements are inapplicable for large-scale teaching purposes due to their laborious preparation process and expense. Fortunately, many phases of the array preparation process can be efficiently demonstrated by using a software simulator tool. Here we propose the use of microarray simulator as an aiding tool in teaching of computational biology. Three case studies on educational use of the simulator are presented, which demonstrate the effect of gene knock-out, synthetic time series, and effect of noise sources. We conclude that the simulator, used for teaching the principles of microarray measurement technology, proved to be a useful tool in education.</description><identifier>ISSN: 1094-687X</identifier><identifier>ISBN: 9781424407873</identifier><identifier>ISBN: 1424407877</identifier><identifier>EISSN: 1558-4615</identifier><identifier>EISBN: 9781424407880</identifier><identifier>EISBN: 1424407885</identifier><identifier>DOI: 10.1109/IEMBS.2007.4353695</identifier><identifier>PMID: 18003361</identifier><language>eng</language><publisher>IEEE</publisher><subject>Analytical models ; Biological information theory ; Biological system modeling ; Computational modeling ; Data analysis ; Education ; Educational technology ; Manufacturing ; Phase measurement ; Phased arrays</subject><ispartof>2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2007, p.5919-5922</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/4353695$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>309,310,780,784,789,790,2058,27925,54920</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/4353695$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc></links><search><creatorcontrib>Ruusuvuori, P.</creatorcontrib><creatorcontrib>Nykter, M.</creatorcontrib><creatorcontrib>Makiraatikka, E.</creatorcontrib><creatorcontrib>Lehmussola, A.</creatorcontrib><creatorcontrib>Korpelainen, T.</creatorcontrib><creatorcontrib>Erkkila, T.</creatorcontrib><creatorcontrib>Yli-Harja, O.</creatorcontrib><title>Microarray Simulator as Educational Tool</title><title>2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society</title><addtitle>IEMBS</addtitle><description>As many real-world applications, microarray measurements are inapplicable for large-scale teaching purposes due to their laborious preparation process and expense. Fortunately, many phases of the array preparation process can be efficiently demonstrated by using a software simulator tool. Here we propose the use of microarray simulator as an aiding tool in teaching of computational biology. Three case studies on educational use of the simulator are presented, which demonstrate the effect of gene knock-out, synthetic time series, and effect of noise sources. We conclude that the simulator, used for teaching the principles of microarray measurement technology, proved to be a useful tool in education.</description><subject>Analytical models</subject><subject>Biological information theory</subject><subject>Biological system modeling</subject><subject>Computational modeling</subject><subject>Data analysis</subject><subject>Education</subject><subject>Educational technology</subject><subject>Manufacturing</subject><subject>Phase measurement</subject><subject>Phased arrays</subject><issn>1094-687X</issn><issn>1558-4615</issn><isbn>9781424407873</isbn><isbn>1424407877</isbn><isbn>9781424407880</isbn><isbn>1424407885</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2007</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><recordid>eNpVkEtPwzAQhM1LtCr5A3DJkUvC-rH2-ghVgEqtOLRI3Co3cSSjlCAnPfTf1xK9MJfRzieNVsPYPYeSc7BPi2r1si4FgCmVRKktXrDMGuJKKAWGCC7ZlCNSoTTHq3_MyOvEwKpCk_masGwYviFJ2oTplk04pUNqPmWPq1DH3sXojvk67A-dG_uYuyGvmkPtxtD_uC7f9H13x25a1w0-O_uMfb5Wm_l7sfx4W8yfl0WQksZCtB4JlUkPa-4RdNu0lELgriZtEGBnGk8CZa3A-lqgAdXKujHcCISdnLGHv97gvd_-xrB38bg9TyBPwoNHMA</recordid><startdate>20070101</startdate><enddate>20070101</enddate><creator>Ruusuvuori, P.</creator><creator>Nykter, M.</creator><creator>Makiraatikka, E.</creator><creator>Lehmussola, A.</creator><creator>Korpelainen, T.</creator><creator>Erkkila, T.</creator><creator>Yli-Harja, O.</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope></search><sort><creationdate>20070101</creationdate><title>Microarray Simulator as Educational Tool</title><author>Ruusuvuori, P. ; Nykter, M. ; Makiraatikka, E. ; Lehmussola, A. ; Korpelainen, T. ; Erkkila, T. ; Yli-Harja, O.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i338t-2fe5854736961e506fdf82fe01ac867500b7de8253c409ec25704f3cd717250b3</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Analytical models</topic><topic>Biological information theory</topic><topic>Biological system modeling</topic><topic>Computational modeling</topic><topic>Data analysis</topic><topic>Education</topic><topic>Educational technology</topic><topic>Manufacturing</topic><topic>Phase measurement</topic><topic>Phased arrays</topic><toplevel>online_resources</toplevel><creatorcontrib>Ruusuvuori, P.</creatorcontrib><creatorcontrib>Nykter, M.</creatorcontrib><creatorcontrib>Makiraatikka, E.</creatorcontrib><creatorcontrib>Lehmussola, A.</creatorcontrib><creatorcontrib>Korpelainen, T.</creatorcontrib><creatorcontrib>Erkkila, T.</creatorcontrib><creatorcontrib>Yli-Harja, O.</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Xplore</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Ruusuvuori, P.</au><au>Nykter, M.</au><au>Makiraatikka, E.</au><au>Lehmussola, A.</au><au>Korpelainen, T.</au><au>Erkkila, T.</au><au>Yli-Harja, O.</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Microarray Simulator as Educational Tool</atitle><btitle>2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society</btitle><stitle>IEMBS</stitle><date>2007-01-01</date><risdate>2007</risdate><spage>5919</spage><epage>5922</epage><pages>5919-5922</pages><issn>1094-687X</issn><eissn>1558-4615</eissn><isbn>9781424407873</isbn><isbn>1424407877</isbn><eisbn>9781424407880</eisbn><eisbn>1424407885</eisbn><abstract>As many real-world applications, microarray measurements are inapplicable for large-scale teaching purposes due to their laborious preparation process and expense. Fortunately, many phases of the array preparation process can be efficiently demonstrated by using a software simulator tool. Here we propose the use of microarray simulator as an aiding tool in teaching of computational biology. Three case studies on educational use of the simulator are presented, which demonstrate the effect of gene knock-out, synthetic time series, and effect of noise sources. We conclude that the simulator, used for teaching the principles of microarray measurement technology, proved to be a useful tool in education.</abstract><pub>IEEE</pub><pmid>18003361</pmid><doi>10.1109/IEMBS.2007.4353695</doi><tpages>4</tpages></addata></record>
fulltext fulltext_linktorsrc
identifier ISSN: 1094-687X
ispartof 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2007, p.5919-5922
issn 1094-687X
1558-4615
language eng
recordid cdi_ieee_primary_4353695
source IEEE Electronic Library (IEL) Conference Proceedings
subjects Analytical models
Biological information theory
Biological system modeling
Computational modeling
Data analysis
Education
Educational technology
Manufacturing
Phase measurement
Phased arrays
title Microarray Simulator as Educational Tool
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T20%3A47%3A01IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-ieee_6IE&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=proceeding&rft.atitle=Microarray%20Simulator%20as%20Educational%20Tool&rft.btitle=2007%2029th%20Annual%20International%20Conference%20of%20the%20IEEE%20Engineering%20in%20Medicine%20and%20Biology%20Society&rft.au=Ruusuvuori,%20P.&rft.date=2007-01-01&rft.spage=5919&rft.epage=5922&rft.pages=5919-5922&rft.issn=1094-687X&rft.eissn=1558-4615&rft.isbn=9781424407873&rft.isbn_list=1424407877&rft_id=info:doi/10.1109/IEMBS.2007.4353695&rft.eisbn=9781424407880&rft.eisbn_list=1424407885&rft_dat=%3Cieee_6IE%3E4353695%3C/ieee_6IE%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-i338t-2fe5854736961e506fdf82fe01ac867500b7de8253c409ec25704f3cd717250b3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/18003361&rft_ieee_id=4353695&rfr_iscdi=true