Spatio-temporal self-calibration of optical dynamical biochip

The authors propose a self-calibration approach to compensate the response dispersion on biochips due to the non homogeneous surface layers. Such effect of probe concentration has been quantified in the case of a DNA biochip.

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Bibliographic Details
Main Authors: Hottin, Jerome, Lecaruyer, Pierre, Spadavecchia, Jolanda, Roger, Gisele, Moreau, Julien, Canva, Michael
Format: Conference Proceeding
Language:English
Subjects:
Biomedical optical imaging
DNA
interaction kinetic monitoring
Kinetic theory
Monitoring
optical biosensor
Optical buffering
Optical imaging
Optical refraction
Plasmons
Probes
Resonance
self-calibration
surface functionalization
surface plasmon resonance imaging
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Description
Summary:The authors propose a self-calibration approach to compensate the response dispersion on biochips due to the non homogeneous surface layers. Such effect of probe concentration has been quantified in the case of a DNA biochip.
DOI:10.1109/CLEOE-IQEC.2007.4386641