Multi-Chip High-Density Microelectrode System for Electrogenic-Cell Recording and Stimulation

An electrogenic-cell-activity monitoring system comprising five high-density CMOS-based microelectrode arrays is presented. Each microelectrode array features 11'016 metal electrodes and 126 on-chip channels for recording and stimulation of the cells. The electrodes are sampled at 20 kHz, and t...

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Main Authors: Sedivy, J., Frey, U., Hafizovic, S., Hierlemann, A.
Format: Conference Proceeding
Language:English
Subjects:
Data processing
Data visualization
Electrodes
Feedback
Field programmable gate arrays
Loss measurement
Microelectrodes
Monitoring
Semiconductor device measurement
Size measurement
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creator Sedivy, J.
Frey, U.
Hafizovic, S.
Hierlemann, A.
description An electrogenic-cell-activity monitoring system comprising five high-density CMOS-based microelectrode arrays is presented. Each microelectrode array features 11'016 metal electrodes and 126 on-chip channels for recording and stimulation of the cells. The electrodes are sampled at 20 kHz, and the signals are converted to the digital domain using an 8-bit AD converter. Further data processing is implemented on a field-programmable gate array (FPGA), which provides realtime feedback and sends the essential information to a PC for storage, visualization and further processing. The system enables to continuously measure at up to 630 electrodes on 5 different chips, it performs loss-less data compression to 15%-50% of the original size and it concurrently detects the spikes generated by the cells.
doi_str_mv 10.1109/ICSENS.2007.4388500
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source IEEE Electronic Library (IEL) Conference Proceedings
subjects Data processing
Data visualization
Electrodes
Feedback
Field programmable gate arrays
Loss measurement
Microelectrodes
Monitoring
Semiconductor device measurement
Size measurement
title Multi-Chip High-Density Microelectrode System for Electrogenic-Cell Recording and Stimulation
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