Novel multifunctional PHDCA/PEI nano-drug carriers for simultaneous magnetically-targeted cancer therapy and diagnosis using magnetic resonance imaging

Novel multifunctional magnetic polycation drug carriers (MPDCs) were synthesized to provide simultaneous magnetically targeted cancer therapy and diagnosis using magnetic resonance imaging (MRI). The MPDCs demonstrated ultra-sensitivity via MRI and sufficient magnetic mobility under an external magn...

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Bibliographic Details
Main Authors: Sungbaek Seo, Jaemoon Yang, Woochan Hyung, Eun-Jin Cho, Yong Jin Song, Ho-Geun Yoon, Jin-Suck Suh, Yong-Min Huh, Seungjoo Haam
Format: Conference Proceeding
Language:English
Subjects:
Cancer
Drugs
Educational institutions
Magnetic fields
Magnetic resonance imaging
Medical treatment
Nanocrystals
Nanoparticles
Saturation magnetization
Solvents
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Summary:Novel multifunctional magnetic polycation drug carriers (MPDCs) were synthesized to provide simultaneous magnetically targeted cancer therapy and diagnosis using magnetic resonance imaging (MRI). The MPDCs demonstrated ultra-sensitivity via MRI and sufficient magnetic mobility under an external magnetic field. Drug loading efficiency and release kinetics were also investigated to assess the therapeutic potential of the MPDCs.
DOI:10.1109/CLEOPR.2007.4391370