Generating controllable microbubbles inside individual cells using femtosecond laser pulses

We demonstrate that microbubbles generated through optical breakdown in tissue phantoms or individual cells are controllable with laser parameters. The controlled microbubbles can be used as an acoustically detectable agent for diagnostic and therapeutic applications.

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Bibliographic Details
Main Authors: Jing Yong Ye, Tse, C., Zohdy, M.J., Hollman, K., Balogh, L., Norris, T.B., O'Donnell, M.
Format: Conference Proceeding
Language:English
Subjects:
(170.1020) Ablation of tissue
(170.7160) Ultrafast technology
(170.7180) Ultrasound diagnostics
Acoustics
Biomedical optical imaging
Lasers
Optical imaging
Optical pulses
Optical reflection
Ultrafast optics
Online Access:Request full text
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Description
Summary:We demonstrate that microbubbles generated through optical breakdown in tissue phantoms or individual cells are controllable with laser parameters. The controlled microbubbles can be used as an acoustically detectable agent for diagnostic and therapeutic applications.
ISSN:2160-9004
DOI:10.1109/CLEO.2006.4628302