Implantable Flexible-Coiled Wireless Intraocular Pressure Sensor

This work presents an implantable wireless passive pressure sensor for long-range continuous intraocular pressure (IOP) monitoring of glaucoma patients. The sensor is microfabricated with use of parylene C (poly-chloro-p-xylylene) to create a flexible coil substrate that can be folded during implant...

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Bibliographic Details
Main Authors: Po-Jui Chen, Saati, S., Varma, R., Humayun, M.S., Yu-Chong Tai
Format: Conference Proceeding
Language:English
Subjects:
Animals
Coils
In vivo
Iris
Minimally invasive surgery
Patient monitoring
Robustness
Sensor phenomena and characterization
Testing
Wireless sensor networks
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Summary:This work presents an implantable wireless passive pressure sensor for long-range continuous intraocular pressure (IOP) monitoring of glaucoma patients. The sensor is microfabricated with use of parylene C (poly-chloro-p-xylylene) to create a flexible coil substrate that can be folded during implantation for suture-less minimally invasive surgery, while stretched back without damage for enhanced inductive sensor-reader coil coupling and the corresponding sensing signal. Extensive device characterizations including on-bench testing and in vivo and ex vivo animal studies verify the device feasibility in both engineering (1 mmHg pressure sensing accuracy and 2 cm sensing distance) and surgical (robust fixation to the iris and long-term biocompatibility in the intraocular environment) aspects, all meeting specifications for future practical implementation of such IOP sensing technology.
ISSN:1084-6999
DOI:10.1109/MEMSYS.2009.4805364