MR-based attenuation correction for a whole-body sequential PET/MR system

In this paper MR-based attenuation method was implemented for a clinical whole-body PET/MR system. While awaiting future clinical evaluation, the algorithm seems promising from preliminary patient data evaluation, from both qualitative PET image quality and quantification accuracy. While the 3-segme...

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Main Authors: Hu, Z., Ojha, N., Renisch, S., Schulz, V., Torres, I., Buhl, A., Pal, D., Muswick, G., Penatzer, J., Guo, T., Bonert, P., Tung, C., Kaste, J., Morich, M., Havens, T., Maniawski, P., Schafer, W., Gunther, R.W., Krombach, G.A., Shao, L.
Format: Conference Proceeding
Language:English
Subjects:
Attenuation
Bones
Coils
Computed tomography
Image segmentation
Lungs
Magnetic resonance imaging
Positron emission tomography
Protons
Whole-body PET
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Summary:In this paper MR-based attenuation method was implemented for a clinical whole-body PET/MR system. While awaiting future clinical evaluation, the algorithm seems promising from preliminary patient data evaluation, from both qualitative PET image quality and quantification accuracy. While the 3-segment MRAC resembles the results from short PET transmission scans, future work will be to implement and validate segmentation of more tissue classes, such as cortical bone. Robustness of MR image truncation compensation and incorporation of flexible coils need to be improved.
ISSN:1082-3654
2577-0829
DOI:10.1109/NSSMIC.2009.5401802