Hybrid nano plasmonics for integrated biosensor

SPR biosensor with OLED and nano-grating for HBV LAMP product detection is reported. Directional emissions by grating-coupler match the resonant condition of SP modes. Concentration changes result in color shift at specific angle. Real time detection of virus load down to 5 copies/25 ul can be achie...

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Bibliographic Details
Main Authors: Lin, Chii-Wann, Lee, Jun-Haw, Chiu, Nan-Fu, Lee, Szu-Yuan, Kou-Chen Liu, Feng-Yu Tsai, Chia-Yu Yen, Lee, Chun-Nan
Format: Conference Proceeding
Language:English
Subjects:
(170.3890) Medical optics instrumentation
(240.6680) Surface plasmons
Biosensors
Electroluminescence
Gratings
Isothermal processes
Lamps
Light sources
Nanostructures
Organic light emitting diodes
Plasmons
Resonance
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Summary:SPR biosensor with OLED and nano-grating for HBV LAMP product detection is reported. Directional emissions by grating-coupler match the resonant condition of SP modes. Concentration changes result in color shift at specific angle. Real time detection of virus load down to 5 copies/25 ul can be achieved in 30 minutes. Surface plasmon Resonant (SPR) biosensor has been used for quantitative measurement of molecular interactions for its advantages of high sensitivity, label-free and real-time detection. In this paper, we report recent efforts on further enhancement of SPR biosensors by the heterogeneous integration of organic electroluminescence light source and nano-grating structure for the feasibility study on the fast and high sensitivity detection of HBV isothermal amplification products, Mg 2 P 2 O 7 . We demonstrated the surface plasmon coupled through hybrid nano-grating structure has highly directional emissions corresponding to the resonant condition of surface plasmon modes on the Au/air interface and controllable plasmonics band-gap by pitch modulation. SPGCE resulted in color change from yellowish green to orange at a certain viewing angle, when contacting glucose with concentration increasing from 10 to 40%.
ISSN:2162-108X
2162-1098