Surface-plasmon enhanced Raman scattering of DNA molecules on regular arrays of modified gold nanoparticles

We performed surface-plasmon enhanced Raman scattering (SERS) studies of a DNA monolayer on chemically modified Au nanoparticle arrays. Drastic enhancement of Raman signal from DNA molecules was observed on the optimized templates that were prepared by using electron-beam lithography followed by che...

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Bibliographic Details
Main Authors: Ho-Jong Kim, Jae-Ho Song, Tae-Soo Kim, Byung-Jun Ahn, Yanqun Dong, Jung-Hoon Song, Sanghun Kim, Hee Jin Sohn, Dong Han Ha
Format: Conference Proceeding
Language:English
Subjects:
Chemical processes
Chemical technology
DNA
Gold
Lithography
Nanoparticles
Optical scattering
Plasmons
Raman scattering
Resonance
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Summary:We performed surface-plasmon enhanced Raman scattering (SERS) studies of a DNA monolayer on chemically modified Au nanoparticle arrays. Drastic enhancement of Raman signal from DNA molecules was observed on the optimized templates that were prepared by using electron-beam lithography followed by chemical modification. We observed that Raman signal of DNA molecules was enhanced when the surface plasmons in the closely-spaced Au nanoparticles were resonantly excited. Our results suggest that the artificial generation of spatially controlled hot spots for SERS can be achieved by this technique.