Development of water-soluble sono/photo-sensitive nanopartices for cancer treatment

Sonodyanmic Therapy (SDT) is a new type of cancer therapy and has attracted lots of research attention recently. In this article, we present how nano-formulation helped SL052 to form a water soluble sono/photo-sensitize nanoparticle (SL052-NPs) for cancer treatment. The nanostructure formation encap...

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Bibliographic Details
Main Authors: Yongde Meng, Chunpu Zou, Min Huang, Jie Chen, Xing, J
Format: Conference Proceeding
Language:English
Subjects:
Absorption
Biomedical imaging
Cancer
Chemicals
Drugs
Medical treatment
Nanobioscience
Nanoparticles
SONOS devices
Ultrasonic imaging
Online Access:Request full text
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Summary:Sonodyanmic Therapy (SDT) is a new type of cancer therapy and has attracted lots of research attention recently. In this article, we present how nano-formulation helped SL052 to form a water soluble sono/photo-sensitize nanoparticle (SL052-NPs) for cancer treatment. The nanostructure formation encapsulates SL052 and greatly improves the SL052 physicochemical properties without modifying its chemical structure. Nano-formulation also helps SL052 to achieve deep-site cancer delivery, image function for diagnosis, and ultrasound or photo controlled localized cancer therapy.
ISSN:0271-4302
2158-1525
DOI:10.1109/ISCAS.2010.5537376