Analysis of threshold influence on the accuracy of gene-prediction methods based on power spectrum analysis

The accuracy of methods based on power spectrum analysis depends on the threshold that is used to discriminate the coding and non-coding sequences. Due to gene structural differences of different organisms, we inferred that there is an optimal gene prediction threshold for each organism. To prove th...

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Bibliographic Details
Main Authors: Shanglei Xu, Nini Rao, Xi Chen, Guangxiong Liu, Yunheng Wang
Format: Conference Proceeding
Language:English
Subjects:
A ver age periodogram
Accuracy
Bioinformatics
DNA
Encoding
gene prediction
Organisms
power spectrum analysis
Proteins
Spectral analysis
threshold
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Summary:The accuracy of methods based on power spectrum analysis depends on the threshold that is used to discriminate the coding and non-coding sequences. Due to gene structural differences of different organisms, we inferred that there is an optimal gene prediction threshold for each organism. To prove this, we analyzed real biological data, and found that there are indeed different optimal thresholds for different organisms when the methods based on power spectrum analysis are used to predict genes.
ISSN:2164-5221
DOI:10.1109/ICOSP.2010.5656377