Porous PLGA microspheres with BMP-2 releasing polyphosphate-functionalized nano-hydroxyapatite for enhanced bone regeneration

We report on bone-regenerative porous microspheres surface-decorated with polyphosphate-functionalized nano-hydroxyapatite (n-HAp) that can controllably release bone morphogenetic protein-2 (BMP-2). n-HAp was immobilized onto the pore surface of microspheres and could control the loading and the rel...

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Bibliographic Details
Main Authors: Ahn Na Koo, Lee, Sang Cheon
Format: Conference Proceeding
Language:English
Subjects:
Adsorption
Biomedical imaging
Polymers
Online Access:Request full text
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Summary:We report on bone-regenerative porous microspheres surface-decorated with polyphosphate-functionalized nano-hydroxyapatite (n-HAp) that can controllably release bone morphogenetic protein-2 (BMP-2). n-HAp was immobilized onto the pore surface of microspheres and could control the loading and the release of BMP-2.
DOI:10.1109/NMDC.2011.6155386