Shape matching with medial curves and 1-D group-wise registration

We present a method for shape matching that approximates group-wise shape registration by reducing the problem to a 1-D registration. First, a novel medial curve method is proposed for computing a 1-D description of the shape. Second, a group-wise registration of the geometric descriptor is performe...

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Bibliographic Details
Main Authors: Gutman, B. A., Yalin Wang, Rajagopalan, P., Toga, A. W., Thompson, P. M.
Format: Conference Proceeding
Language:English
Subjects:
ADNI
Biomedical imaging
Geometry
group-wise registration
Human immunodeficiency virus
medial curves
Optical fibers
Shape
shape registration
skeletonization
Statistical analysis
Thickness measurement
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Description
Summary:We present a method for shape matching that approximates group-wise shape registration by reducing the problem to a 1-D registration. First, a novel medial curve method is proposed for computing a 1-D description of the shape. Second, a group-wise registration of the geometric descriptor is performed by directly minimizing the group variance. The resulting registration is used to adjust a global shape feature used to compute the final correspondence. Thus, the problems of description, registration, and statistical analysis are solved in one framework, while reducing the computational problem of group-wise registration of shapes substantially. We validate our method on 620 lateral ventricles extracted from the ADNI MRI dataset and 19 lateral ventricles from patients with HIV/AIDS and matched controls, also scanned with MRI. We show that our group-wise approach leads to improved statistical results, and also compare it to the SPHARM method.
ISSN:1945-7928
1945-8452
DOI:10.1109/ISBI.2012.6235648