Infrared photon discrimination of lung cancer cells

The objective of this study is to explore the polarimetric phenomenology of near infrared light interaction with healthy and lung cancer monolayer cells by using efficient polarimetric transmission detection techniques. Preliminary results indicate that enhanced discrimination between normal and dif...

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Main Authors: Giakos, G. C., Shrestha, S., Petermann, J., Narayan, C., Marotta, S., Despande, A., Syms, J., Farrahi, T., Blinzler, A., Picard, R. H., Inbody, W., Dao, P. D., Crabtree, P. N., McNicholl, P. J., Zhang, L., Zhou, A., Zervakis, M., Kounelakis, M. G., Bei, E. S., Livanos, G.
Format: Conference Proceeding
Language:English
Subjects:
Adenocarcinoma
Cancer
Efficient discrimination
Generators
Geometry
Heating
Laser modes
Lead
Lung squamous carcinoma
Measurement by laser beam
Mixture of cancer cells
Near infrared light
nuclei size
nucleus-to-cytoplasmatic ratio
Polarimetric phenomenology
Polarization signatures
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Summary:The objective of this study is to explore the polarimetric phenomenology of near infrared light interaction with healthy and lung cancer monolayer cells by using efficient polarimetric transmission detection techniques. Preliminary results indicate that enhanced discrimination between normal and different types of lung cancer cell stages can be achieved based on their transmitted intensities and depolarization properties of the cells. Specifically, the sizes of the nuclei of the cancer cells and the nucleus-to-cytoplasmic ratios appear to have potential impact on the detected polarimetric signatures leading to enhanced discrimination of lung cancer cells.
ISSN:1558-2809
2832-4242
DOI:10.1109/IST.2012.6295599