A super-resolution CMOS image sensor for bio-microfluidic imaging

A super-resolution CMOS image sensor is introduced in this paper for bio-microfluidic imaging. Compared to the traditional scientific CCD or CMOS image sensor, our design achieves the balance between high-sensitivity and high-resolution from system design perspective with the use of single-frame sup...

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Bibliographic Details
Main Authors: Tongxi Wang, Xiwei Huang, Qixiang Jia, Mei Yan, Hao Yu, Kiat Seng Yeo
Format: Conference Proceeding
Language:English
Subjects:
Biomedical imaging
CMOS image sensors
Signal resolution
Spatial resolution
System-on-a-chip
Online Access:Request full text
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Description
Summary:A super-resolution CMOS image sensor is introduced in this paper for bio-microfluidic imaging. Compared to the traditional scientific CCD or CMOS image sensor, our design achieves the balance between high-sensitivity and high-resolution from system design perspective with the use of single-frame super-resolution. Moreover, the column-parallel image sensor architecture with correlated-double-sampling is deployed for high-speed and low-noise readout. The chip is designed in standard 0.18μm CMOS mixed-signal process with area of 2.5mm×5.0mm, 128×128 pixel-array and speed of 1750 frames/s. The resolution is improved by 4X by on-chip super-resolution algorithm while large pixel (10μm×10μm) is employed in image sensor for high-sensitivity.
ISSN:2163-4025
2766-4465
DOI:10.1109/BioCAS.2012.6418415