Integrated optrode array for neural stimulating and recording

We present the design, fabrication, simulation and characterization of a novel optrode array for light delivery and neural recording on animal optogenetic experiment in vivo. With the help of a MT connector, the optrode was arranged into 1×6 linear array and can be firmly and simply connected to opt...

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Bibliographic Details
Main Authors: SanYuan Chen, WeiHua Pei, Qiang Gui, Hui Zhao, YuanFang Chen, HongDa Chen
Format: Conference Proceeding
Language:English
Subjects:
Arrays
Optical device fabrication
Optical fiber devices
Optical fibers
Optical recording
Stimulated emission
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Summary:We present the design, fabrication, simulation and characterization of a novel optrode array for light delivery and neural recording on animal optogenetic experiment in vivo. With the help of a MT connector, the optrode was arranged into 1×6 linear array and can be firmly and simply connected to optical source. The optrode was fabricated from a fiber. Fiber tip is tapered by wet etching. Au/Cr film is deposited,insulated by parylene and exposed at the tip by RIE to integrate electrical recording sites on one side of the fiber. The typical impedance at 1 KHz and output power of the optrode is 80KΩ and 13mw when evaluated in vitro. Acute animal implant experiment shows the optrode can work well in ChR2 transgenic mice.
ISSN:2163-4025
2766-4465
DOI:10.1109/BioCAS.2012.6418463