Integrated optrode array for neural stimulating and recording

We present the design, fabrication, simulation and characterization of a novel optrode array for light delivery and neural recording on animal optogenetic experiment in vivo. With the help of a MT connector, the optrode was arranged into 1×6 linear array and can be firmly and simply connected to opt...

Full description

Saved in:
Bibliographic Details
Main Authors: SanYuan Chen, WeiHua Pei, Qiang Gui, Hui Zhao, YuanFang Chen, HongDa Chen
Format: Conference Proceeding
Language:English
Subjects:
Arrays
Optical device fabrication
Optical fiber devices
Optical fibers
Optical recording
Stimulated emission
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page 199
container_issue
container_start_page 196
container_title
container_volume
creator SanYuan Chen
WeiHua Pei
Qiang Gui
Hui Zhao
YuanFang Chen
HongDa Chen
description We present the design, fabrication, simulation and characterization of a novel optrode array for light delivery and neural recording on animal optogenetic experiment in vivo. With the help of a MT connector, the optrode was arranged into 1×6 linear array and can be firmly and simply connected to optical source. The optrode was fabricated from a fiber. Fiber tip is tapered by wet etching. Au/Cr film is deposited,insulated by parylene and exposed at the tip by RIE to integrate electrical recording sites on one side of the fiber. The typical impedance at 1 KHz and output power of the optrode is 80KΩ and 13mw when evaluated in vitro. Acute animal implant experiment shows the optrode can work well in ChR2 transgenic mice.
doi_str_mv 10.1109/BioCAS.2012.6418463
format conference_proceeding
fullrecord <record><control><sourceid>ieee_CHZPO</sourceid><recordid>TN_cdi_ieee_primary_6418463</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ieee_id>6418463</ieee_id><sourcerecordid>6418463</sourcerecordid><originalsourceid>FETCH-LOGICAL-i175t-3c5fc4fcde3de9006a1982e428d49c1349bdd3e2e99658d3eeddcb3e869193423</originalsourceid><addsrcrecordid>eNo1kL1OwzAUhc2fRCl5gi5-gQTfa8exB4YSFahUiQGYKze-qYzSpHLcoW9PJMp0vqNPOsNhbAGiABD26SUM9fKzQAFYaAVGaXnFMlsZULqSiBbNNZthpXWulC5v2MO_ALidBGiZK4HlPcvG8UcIAdqgEXrGntd9on10iTwfjikOnriL0Z15O0Te0ym6jo8pHE6dS6Hfc9d7HqkZop_aI7trXTdSdsk5-35dfdXv-ebjbV0vN3mAqky5bMq2UW3jSXqyQmgH1iApNF7ZBqSyO-8lIVmrSzMRed_sJBltwUqFcs4Wf7uBiLbHGA4unreXJ-QvU-1Osw</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>conference_proceeding</recordtype></control><display><type>conference_proceeding</type><title>Integrated optrode array for neural stimulating and recording</title><source>IEEE Xplore All Conference Series</source><creator>SanYuan Chen ; WeiHua Pei ; Qiang Gui ; Hui Zhao ; YuanFang Chen ; HongDa Chen</creator><creatorcontrib>SanYuan Chen ; WeiHua Pei ; Qiang Gui ; Hui Zhao ; YuanFang Chen ; HongDa Chen</creatorcontrib><description>We present the design, fabrication, simulation and characterization of a novel optrode array for light delivery and neural recording on animal optogenetic experiment in vivo. With the help of a MT connector, the optrode was arranged into 1×6 linear array and can be firmly and simply connected to optical source. The optrode was fabricated from a fiber. Fiber tip is tapered by wet etching. Au/Cr film is deposited,insulated by parylene and exposed at the tip by RIE to integrate electrical recording sites on one side of the fiber. The typical impedance at 1 KHz and output power of the optrode is 80KΩ and 13mw when evaluated in vitro. Acute animal implant experiment shows the optrode can work well in ChR2 transgenic mice.</description><identifier>ISSN: 2163-4025</identifier><identifier>ISBN: 1467322911</identifier><identifier>ISBN: 9781467322911</identifier><identifier>EISSN: 2766-4465</identifier><identifier>EISBN: 9781467322928</identifier><identifier>EISBN: 146732292X</identifier><identifier>EISBN: 1467322938</identifier><identifier>EISBN: 9781467322935</identifier><identifier>DOI: 10.1109/BioCAS.2012.6418463</identifier><language>eng</language><publisher>IEEE</publisher><subject>Arrays ; Optical device fabrication ; Optical fiber devices ; Optical fibers ; Optical recording ; Stimulated emission</subject><ispartof>2012 IEEE Biomedical Circuits and Systems Conference (BioCAS), 2012, p.196-199</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/6418463$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>309,310,780,784,789,790,2057,27924,54554,54919,54931</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/6418463$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc></links><search><creatorcontrib>SanYuan Chen</creatorcontrib><creatorcontrib>WeiHua Pei</creatorcontrib><creatorcontrib>Qiang Gui</creatorcontrib><creatorcontrib>Hui Zhao</creatorcontrib><creatorcontrib>YuanFang Chen</creatorcontrib><creatorcontrib>HongDa Chen</creatorcontrib><title>Integrated optrode array for neural stimulating and recording</title><title>2012 IEEE Biomedical Circuits and Systems Conference (BioCAS)</title><addtitle>BioCAS</addtitle><description>We present the design, fabrication, simulation and characterization of a novel optrode array for light delivery and neural recording on animal optogenetic experiment in vivo. With the help of a MT connector, the optrode was arranged into 1×6 linear array and can be firmly and simply connected to optical source. The optrode was fabricated from a fiber. Fiber tip is tapered by wet etching. Au/Cr film is deposited,insulated by parylene and exposed at the tip by RIE to integrate electrical recording sites on one side of the fiber. The typical impedance at 1 KHz and output power of the optrode is 80KΩ and 13mw when evaluated in vitro. Acute animal implant experiment shows the optrode can work well in ChR2 transgenic mice.</description><subject>Arrays</subject><subject>Optical device fabrication</subject><subject>Optical fiber devices</subject><subject>Optical fibers</subject><subject>Optical recording</subject><subject>Stimulated emission</subject><issn>2163-4025</issn><issn>2766-4465</issn><isbn>1467322911</isbn><isbn>9781467322911</isbn><isbn>9781467322928</isbn><isbn>146732292X</isbn><isbn>1467322938</isbn><isbn>9781467322935</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2012</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><recordid>eNo1kL1OwzAUhc2fRCl5gi5-gQTfa8exB4YSFahUiQGYKze-qYzSpHLcoW9PJMp0vqNPOsNhbAGiABD26SUM9fKzQAFYaAVGaXnFMlsZULqSiBbNNZthpXWulC5v2MO_ALidBGiZK4HlPcvG8UcIAdqgEXrGntd9on10iTwfjikOnriL0Z15O0Te0ym6jo8pHE6dS6Hfc9d7HqkZop_aI7trXTdSdsk5-35dfdXv-ebjbV0vN3mAqky5bMq2UW3jSXqyQmgH1iApNF7ZBqSyO-8lIVmrSzMRed_sJBltwUqFcs4Wf7uBiLbHGA4unreXJ-QvU-1Osw</recordid><startdate>201211</startdate><enddate>201211</enddate><creator>SanYuan Chen</creator><creator>WeiHua Pei</creator><creator>Qiang Gui</creator><creator>Hui Zhao</creator><creator>YuanFang Chen</creator><creator>HongDa Chen</creator><general>IEEE</general><scope>6IE</scope><scope>6IL</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIL</scope></search><sort><creationdate>201211</creationdate><title>Integrated optrode array for neural stimulating and recording</title><author>SanYuan Chen ; WeiHua Pei ; Qiang Gui ; Hui Zhao ; YuanFang Chen ; HongDa Chen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i175t-3c5fc4fcde3de9006a1982e428d49c1349bdd3e2e99658d3eeddcb3e869193423</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Arrays</topic><topic>Optical device fabrication</topic><topic>Optical fiber devices</topic><topic>Optical fibers</topic><topic>Optical recording</topic><topic>Stimulated emission</topic><toplevel>online_resources</toplevel><creatorcontrib>SanYuan Chen</creatorcontrib><creatorcontrib>WeiHua Pei</creatorcontrib><creatorcontrib>Qiang Gui</creatorcontrib><creatorcontrib>Hui Zhao</creatorcontrib><creatorcontrib>YuanFang Chen</creatorcontrib><creatorcontrib>HongDa Chen</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan All Online (POP All Online) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP All) 1998-Present</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SanYuan Chen</au><au>WeiHua Pei</au><au>Qiang Gui</au><au>Hui Zhao</au><au>YuanFang Chen</au><au>HongDa Chen</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Integrated optrode array for neural stimulating and recording</atitle><btitle>2012 IEEE Biomedical Circuits and Systems Conference (BioCAS)</btitle><stitle>BioCAS</stitle><date>2012-11</date><risdate>2012</risdate><spage>196</spage><epage>199</epage><pages>196-199</pages><issn>2163-4025</issn><eissn>2766-4465</eissn><isbn>1467322911</isbn><isbn>9781467322911</isbn><eisbn>9781467322928</eisbn><eisbn>146732292X</eisbn><eisbn>1467322938</eisbn><eisbn>9781467322935</eisbn><abstract>We present the design, fabrication, simulation and characterization of a novel optrode array for light delivery and neural recording on animal optogenetic experiment in vivo. With the help of a MT connector, the optrode was arranged into 1×6 linear array and can be firmly and simply connected to optical source. The optrode was fabricated from a fiber. Fiber tip is tapered by wet etching. Au/Cr film is deposited,insulated by parylene and exposed at the tip by RIE to integrate electrical recording sites on one side of the fiber. The typical impedance at 1 KHz and output power of the optrode is 80KΩ and 13mw when evaluated in vitro. Acute animal implant experiment shows the optrode can work well in ChR2 transgenic mice.</abstract><pub>IEEE</pub><doi>10.1109/BioCAS.2012.6418463</doi><tpages>4</tpages></addata></record>
fulltext fulltext_linktorsrc
identifier ISSN: 2163-4025
ispartof 2012 IEEE Biomedical Circuits and Systems Conference (BioCAS), 2012, p.196-199
issn 2163-4025
2766-4465
language eng
recordid cdi_ieee_primary_6418463
source IEEE Xplore All Conference Series
subjects Arrays
Optical device fabrication
Optical fiber devices
Optical fibers
Optical recording
Stimulated emission
title Integrated optrode array for neural stimulating and recording
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T14%3A41%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-ieee_CHZPO&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=proceeding&rft.atitle=Integrated%20optrode%20array%20for%20neural%20stimulating%20and%20recording&rft.btitle=2012%20IEEE%20Biomedical%20Circuits%20and%20Systems%20Conference%20(BioCAS)&rft.au=SanYuan%20Chen&rft.date=2012-11&rft.spage=196&rft.epage=199&rft.pages=196-199&rft.issn=2163-4025&rft.eissn=2766-4465&rft.isbn=1467322911&rft.isbn_list=9781467322911&rft_id=info:doi/10.1109/BioCAS.2012.6418463&rft.eisbn=9781467322928&rft.eisbn_list=146732292X&rft.eisbn_list=1467322938&rft.eisbn_list=9781467322935&rft_dat=%3Cieee_CHZPO%3E6418463%3C/ieee_CHZPO%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-i175t-3c5fc4fcde3de9006a1982e428d49c1349bdd3e2e99658d3eeddcb3e869193423%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rft_ieee_id=6418463&rfr_iscdi=true