Contactless characterization of yeast cell cultivation at 7 GHz and 240 GHz

Experimental results of contactless and label-free characterization techniques of cell cultivation are presented. The two demonstrated approaches are compared at two frequencies, 7 GHz and 240 GHz in terms of sensitivity and applicability. At 7 GHz, measurements have been performed using a rat-race...

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Bibliographic Details
Main Authors: Wessel, J., Schmalz, K., Cahill, B. P., Gastrock, G., Meliani, C.
Format: Conference Proceeding
Language:English
Subjects:
Amplitudes
biosensor
Biosensors
Cultivation
label-free
Meetings
microfluidic
Microfluidics
microwave
Microwave measurement
Microwave theory and techniques
Monitoring
Permittivity
Photoconductivity
Pipe
Silicon
sub-THz
Sugar
Tubes
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Summary:Experimental results of contactless and label-free characterization techniques of cell cultivation are presented. The two demonstrated approaches are compared at two frequencies, 7 GHz and 240 GHz in terms of sensitivity and applicability. At 7 GHz, measurements have been performed using a rat-race based characterizing system. Furthermore, the sensitivity of spectroscopy measurements at 240 GHz has been compared for two extracted parameters: phase and amplitude. The conducted experiments demonstrate that by selecting the proper characterization parameter, the presented techniques are suitable for cell cultivation monitoring in a pipe based microfluidic system with PTFE tubes. Especially, the use of higher frequencies enables a higher compactness.
DOI:10.1109/SiRF.2013.6489461