Spectroscopy and pH biosensors for the detection of gastrointestinal dysplasia

The key to successful treatment of gastrointestinal (GI) cancer is the ability to detect the cancer at its earliest stages, called "dysplasia". Optical techniques may considerably improve the ability to detect dysplasia as they have the potential to provide morphological and biochemical in...

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Bibliographic Details
Main Authors: Pimenta, S., Monteiro, T. S., Goncalves, L. M., Minas, G.
Format: Conference Proceeding
Language:English
Subjects:
Biomedical optical imaging
Biosensors
Diffuse reflectance spectroscopy
Fluorescence spectroscopy
Gastrointestinal cancer
ISFET
Measurement by laser beam
Optical fibers
Optical surface waves
Optical variables measurement
pH biosensors
Reflectivity
Science & Technology
Silicon micro electrodes
Silicon microelectrodes
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Summary:The key to successful treatment of gastrointestinal (GI) cancer is the ability to detect the cancer at its earliest stages, called "dysplasia". Optical techniques may considerably improve the ability to detect dysplasia as they have the potential to provide morphological and biochemical information of normal and diseased tissue. The proposed research project relies in the development of a chip-sized spectroscopy microsystem for the detection of morphological and biochemical tissue changes. Moreover, pH biosensors will be developed, and incorporated on the same chip, which will add essential diagnostic information as a complement to spectroscopy.
DOI:10.1109/ENBENG.2013.6518407