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Complexity of autonomic control during cerebrovascular reactivity

Complexity of autonomic regulation affects the systemic vascular, but little is known about its influence on cerebrovascular regulation. In this study, we examine the complexity of neuromodulation by frequency and nonlinear heart rate variability (HRV) to cerebral reserve function during cerebrovasc...

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Bibliographic Details
Main Authors: Intharakham, Kannakorn, Suwanprasert, Kesorn
Format: Conference Proceeding
Language:English
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Summary:Complexity of autonomic regulation affects the systemic vascular, but little is known about its influence on cerebrovascular regulation. In this study, we examine the complexity of neuromodulation by frequency and nonlinear heart rate variability (HRV) to cerebral reserve function during cerebrovascular reactivity (CVR) by breath holding induced - hypercapnia and subsequently, cerebral vasodilatation. Method: 16 healthy controls were monitored during CVR for arterial blood pressure (ABP), electrocardiography (EKG) and mean cerebral blood flow velocity (mCBFV) of middle cerebral arteries (MCA) with transcranial Doppler. Short term-one minute HRV was analyzed for LF/HF ratio, nonlinear of SD1/SD2 and SampEn. Result: An increase in LF/HF ratio from 0.79 ± 0.85 to 2.05 ± 1.38 (p
DOI:10.1109/BMEiCon.2013.6687679