Temporal evolution of spatial regularity in ventricular fibrillation modified by physical exercise

This study analyses the modifications produced by physical exercise in cardiac mapping recordings during Ventricular Fibrillation (VF), compared to the ones produced by Glibenclamide. Three groups of rabbits were used. Gl: control (sedentary rabbits), G2: trained (rabbits submitted to a running prog...

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Bibliographic Details
Main Authors: Caravaca, Juan, Serrano-Lopez, Antonio J., Soria-Olivas, Emilio, Bataller, Manuel, Rosado-Munoz, Alfredo, Such-Belenguer, Luis, Guerrero, Juan F.
Format: Conference Proceeding
Language:English
Subjects:
Abstracts
Electrodes
Heart
Three-dimensional displays
Training
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Summary:This study analyses the modifications produced by physical exercise in cardiac mapping recordings during Ventricular Fibrillation (VF), compared to the ones produced by Glibenclamide. Three groups of rabbits were used. Gl: control (sedentary rabbits), G2: trained (rabbits submitted to a running program) and G3: drugged (sedentary rabbits treated with Glibenclamide). VF was induced during each experiment, and two recordings were acquired: maintained perfusion and ischemic damage. The recordings were analysed in consecutive 4-second segments and Regularity Index (RJ) was obtained for every segment and lead. RJ quantifies the morphological regularity among local activation waves found in a lead. A map with the RI value in each electrode was computed for each segment. In order to analyse the spatial distribution of RL Regions Of Interest (ROI) were obtained. Two parameters were calculated: ROI spatial number (ROlsn, a measure of spatial fragmentation), and ROI spatial area (ROlsa, the percentage of area map occupied by ROI). Control group has shown higher values of ROlsn than trained and drugged groups (p
ISSN:0276-6574
2325-8853