Clinical detection of viral infection on an optofluidic chip

We demonstrate strain-specific detection of single virus nucleic acid molecules from clinical influenza samples using an optofluidic chip. We observe a limit of detection of 10 4 virus copies/mL and 10 orders of magnitude dynamic range.

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Main Authors: Measor, P., Zempoaltecatl, L. U., Parks, J. W., Naccache, S., Miller, S., Chiu, C. Y., Hawkins, A. R., Schmidt, H.
Format: Conference Proceeding
Language:English
Subjects:
Biomedical optical imaging
Educational institutions
Influenza
Medical diagnostic imaging
Optical sensors
Optical waveguides
Probes
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creator Measor, P.
Zempoaltecatl, L. U.
Parks, J. W.
Naccache, S.
Miller, S.
Chiu, C. Y.
Hawkins, A. R.
Schmidt, H.
description We demonstrate strain-specific detection of single virus nucleic acid molecules from clinical influenza samples using an optofluidic chip. We observe a limit of detection of 10 4 virus copies/mL and 10 orders of magnitude dynamic range.
doi_str_mv 10.1364/CLEO_SI.2013.CM1M.7
format conference_proceeding
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source IEEE Xplore All Conference Series
subjects Biomedical optical imaging
Educational institutions
Influenza
Medical diagnostic imaging
Optical sensors
Optical waveguides
Probes
title Clinical detection of viral infection on an optofluidic chip
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