A novel amperometric sensor readout based on charge measurement by current integration

In this paper, a 3-electrode amperometric sensor readout circuit that can be used for multiple electrochemical sensor cells with an embedded integrator for charge determination is presented. The circuit consists of a wide current range amperometric sensor readout circuit that utilizes a PMOS source...

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Bibliographic Details
Main Authors: Wen-Yaw Chung, Silverio, Angelito A., Zhou Ming-Ying, Tsai, Vincent F. S.
Format: Conference Proceeding
Language:English
Subjects:
Amperometric Sensor Readout
Amperometric sensors
Biosensors
Current Integration
Electrodes
Immune system
Integrated circuit modeling
Mirrors
Pass Transistor
Potentiostat
Second Generation Current Conveyor
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Description
Summary:In this paper, a 3-electrode amperometric sensor readout circuit that can be used for multiple electrochemical sensor cells with an embedded integrator for charge determination is presented. The circuit consists of a wide current range amperometric sensor readout circuit that utilizes a PMOS source at the input thereby providing low input impedance. The circuit also has PMOS pass elements for Working Electrode (WE) selection. The front-end is coupled to a current integrator circuit formed by a Second Generation Current Conveyor (CCII) which gives the amount of charge generated over time by the redox reaction. Pre-layout simulations are carried out using HSPICE G2012.06. The circuit was implemented using TSMC 0.35um Mixed Mode CMOS Process.
ISSN:2325-0631
DOI:10.1109/ISICIR.2014.7029463