Quantitative modelling of growth and metabolism of CHO-K1 cell cultures in a serum free medium

A quantitative model of growth and metabolism of CH0-K1 cell culture in a serum-free medium is presented. The model is validated using five batch experiments with varying glucose and glutamine initial concentrations.

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Bibliographic Details
Main Authors: Nasution, U., Verhoeye, F., Bastin, G., Agathos, S., Schneider, Y.-J
Format: Conference Proceeding
Language:English
Subjects:
Amino acids
bioprocess modelling
Biotechnology
Equations
Estimation
Glucose
Glutamine
kinetic parameter
Mathematical model
Metabolism
Modelling
Proteins
Serums
Sugar
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Description
Summary:A quantitative model of growth and metabolism of CH0-K1 cell culture in a serum-free medium is presented. The model is validated using five batch experiments with varying glucose and glutamine initial concentrations.
DOI:10.23919/ECC.2001.7076307