A cannula-based computational fluorescence microscope for neuronal imaging

We applied nonlinear optimization to convert a cannula into a high-resolution computational-fluorescence microscope. The microscope was used to image fluorescent microspheres, genetically-encoded mouse-brain slices, genetically-encoded and fluorescent-stained C. elegans nematodes (both living and de...

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Bibliographic Details
Main Authors: Ganghun Kim, Nagarajan, Naveen, Meiri, Amihai, Merrill, Sean, Capecchi, Mario, Jorgensen, Erik M., Menon, Rajesh
Format: Conference Proceeding
Language:English
Subjects:
Cities and towns
Fluorescence
Image reconstruction
Image resolution
Microscopy
Optical microscopy
Online Access:Request full text
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Summary:We applied nonlinear optimization to convert a cannula into a high-resolution computational-fluorescence microscope. The microscope was used to image fluorescent microspheres, genetically-encoded mouse-brain slices, genetically-encoded and fluorescent-stained C. elegans nematodes (both living and dead animals).
ISSN:2160-8989
2160-9004