Study on Active Components on Sleep-Improving Function of Compound Prescription of Valeriana Officinalis

In this paper, Experiments were carried out on mice with valerian complexes(Valerian officinal is, Ziziphus jujuba Mill. Var. Spinosa (Bunge), platycladi seed), detection of its active components to improve sleep. Direct sleep experiment method as the evaluation index to discuss effects of sedative...

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Bibliographic Details
Main Authors: Li-Hui Zhao, Feng-Qi Hao, Yu-juan Chen, De-ming Han
Format: Conference Proceeding
Language:English
Subjects:
active component
Aqueous extract
Compounds
Drug delivery
Drugs
Improving sleep
Life sciences
Mice
Switching circuits
Valerian compound
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Summary:In this paper, Experiments were carried out on mice with valerian complexes(Valerian officinal is, Ziziphus jujuba Mill. Var. Spinosa (Bunge), platycladi seed), detection of its active components to improve sleep. Direct sleep experiment method as the evaluation index to discuss effects of sedative and sleeping of valerian extract water, valerian compound prescription and their respective extraction component. Valerian aqueous extract, compound preparation, valerian extract and ethyl acetate extract phase and the water extract of nbutanol extraction phase can Being shorten the sleep latency of mice, prolong the sleeping time of mice, no tolerance. The nbutanol extract of Valerian a water phase to shorten the sleep latency of mice, it is the best effect to prolong the sleeping time of mice.
ISSN:2157-1473
DOI:10.1109/ICMTMA.2015.254