A fast model for simulating reentry in three dimensions with fiber rotation

Transmural rotation of cardiac fibers may have a large influence on reentry in the heart. However, modeling reentry is computationally challenging since the tissue modeled must be large enough to sustain reentry and this leads to a system of with millions of variables. A method is presented which de...

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Bibliographic Details
Main Authors: Vigmond, E.J., Leon, L.J.
Format: Conference Proceeding
Language:English
Subjects:
Anisotropic magnetoresistance
Cardiac tissue
Computational modeling
Concurrent computing
Finite difference methods
Heart
Muscles
Optical fiber cables
Pathology
Time measurement
Online Access:Request full text
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Summary:Transmural rotation of cardiac fibers may have a large influence on reentry in the heart. However, modeling reentry is computationally challenging since the tissue modeled must be large enough to sustain reentry and this leads to a system of with millions of variables. A method is presented which decreases computation time due to its use of a discrete cable model which allows for system order reduction, and because it tracks the activation wavefront and only integrates the neighborhood of the front with a small time step. Simulations of approximately 1.8/spl times/10/sup 6/ cells in a block measuring 2/spl times/4/spl times/0.29 cm were possible in a reasonable amount of time. The effect on speed and accuracy of model parameters is discussed. It is also demonstrated that the method lends itself well to parallel computation. The effect of fiber rotation can be clearly seen during reentry.
ISSN:1094-687X
1558-4615
DOI:10.1109/IEMBS.1998.745814