In vivo detection of normal and pathologic bowel electrical activity using a SQUID magnetometer

The Superconducting QUantum Interference Device (SQUID) magnetometer can non-invasively detect the magnetic fields created by the Basic Electrical Rhythm (BER) of the Gastrointestinal Tract (GIT). Using anesthetized adult male New Zealand rabbits the authors recorded signals from two isolated bowel...

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Bibliographic Details
Main Authors: Ladipo, J.K., Bradshaw, L.A., Hegde, S.S., Wikswo, J.P., Richards, W.O.
Format: Conference Proceeding
Language:English
Subjects:
Bit error rate
Frequency
Gastrointestinal tract
In vivo
Interference
Magnetic fields
Rabbits
Rhythm
SQUID magnetometers
Superconducting devices
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Summary:The Superconducting QUantum Interference Device (SQUID) magnetometer can non-invasively detect the magnetic fields created by the Basic Electrical Rhythm (BER) of the Gastrointestinal Tract (GIT). Using anesthetized adult male New Zealand rabbits the authors recorded signals from two isolated bowel segments at the same time, before and after ischemia was induced in either one or both bowel segments. The dominant frequency peaks for each period of recording were determined using autoregressive (AR) spectral analysis. There was a significant fall in the BER frequency in the ischemic segment from 11.8/spl plusmn/0.9 to 7.8/spl plusmn/0.6 cycles per minute (cpm), while there was no change in the normal bowel. It was possible for two observers (LAB, WOR) who were blinded to the preparation, to identify which bowel segment was ischemic. The results of this experiment demonstrate the ability of the SQUID magnetometer to noninvasively detect and differentiate signals from normal and ischemic bowel sources.
ISSN:1094-687X
1558-4615
DOI:10.1109/IEMBS.1997.756799