PET attenuation correction using mean attenuation coefficients: a simulation study

It is desirable to use mean population attenuation coefficients to reduce the statistical fluctuations in measured attenuation maps. In addition, the use of mean attenuation coefficients is also expected to facilitate algorithmic approaches to attenuation correction. Because of the large variation i...

Full description

Saved in:
Bibliographic Details
Published in:IEEE transactions on nuclear science 1999-12, Vol.46 (6), p.2172-2176
Main Author: Madsen, M.T.
Format: Article
Language:English
Subjects:
Attenuation
Attenuation measurement
Cardiovascular system
Cities and towns
Computer simulation
Fluctuations
Heart
Image reconstruction
Lungs
Measurement errors
Myocardium
Positron emission tomography
Statistical methods
Testing
Thorax
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:It is desirable to use mean population attenuation coefficients to reduce the statistical fluctuations in measured attenuation maps. In addition, the use of mean attenuation coefficients is also expected to facilitate algorithmic approaches to attenuation correction. Because of the large variation in lung attenuation coefficients both within and among individuals, there is concern about the errors using mean attenuation might create. To test the magnitude of this problem, myocardial metabolic studies were simulated. Attenuated projections were generated from 20 emission and transmission distributions spanning the heart volume. The projections were corrected with both the actual attenuation map and with a mean attenuation map. Quantitative comparisons of the reconstructed images demonstrate no significant differences in the myocardial distributions. However, errors in the lung field exceeded 300% in some regions.
ISSN:0018-9499
1558-1578
DOI:10.1109/23.819300