Differential method for undisturbed detection of 17β-estradiol using an integrated aptameric graphene nanosensor

This paper presents a differential method based on the graphene field effect biosensor for the rapid and specific quantification of environmental pollution-related biochemical analyte. Selectively functionalizing one of the two identical graphene channels and calibrating the sensitivity difference o...

Full description

Saved in:
Bibliographic Details
Main Authors: Li, Yijun, Zhu, Yibo, Hao, Zhuang, Wang, Cheng, Zhang, Zhixing, He, Miao, Lin, Qiao
Format: Conference Proceeding
Language:English
Subjects:
Biosensors
Field effect transistors
Graphene
Microfluidics
Sensitivity
Testing
Transconductance
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page 296
container_issue
container_start_page 293
container_title
container_volume
creator Li, Yijun
Zhu, Yibo
Hao, Zhuang
Wang, Cheng
Zhang, Zhixing
He, Miao
Lin, Qiao
description This paper presents a differential method based on the graphene field effect biosensor for the rapid and specific quantification of environmental pollution-related biochemical analyte. Selectively functionalizing one of the two identical graphene channels and calibrating the sensitivity difference of the two channels allowed us to extract analyte binding-induced signals by subtracting irregular and unpredictable background. Using this method we demonstrated real-time monitoring of 17β-estradiol in electrolytes with varying pH value. This work represents important progress of graphene field effect sensors toward use with complex real samples.
doi_str_mv 10.1109/MEMSYS.2018.8346543
format conference_proceeding
fullrecord <record><control><sourceid>ieee_CHZPO</sourceid><recordid>TN_cdi_ieee_primary_8346543</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ieee_id>8346543</ieee_id><sourcerecordid>8346543</sourcerecordid><originalsourceid>FETCH-LOGICAL-i175t-33137c9ea7c09637a2cde6942019b668610b3c8ab58538d693492cbf7ee28323</originalsourceid><addsrcrecordid>eNotUM1qAjEYTAuFivUJvOQF1uZLdvNzLNb-gNKDXnqSbPKtpmjWJvHQ1-qD9Jm6oHMZGIZhZgiZApsBMPO4WqzWn-sZZ6BnWtSyqcUNmRiloRFa1kpzdktGHCSrwEh9TyY5f7EBpubAYUS-n0PXYcJYgj3QI5Z972nXJ3qOPuRyTi166rGgK6GPtO8oqL_fCnNJ1of-QM85xB21kYZYcJdsGfz2VOwRU3B0EE57jEijjX3GmPv0QO46e8g4ufKYbF4Wm_lbtfx4fZ8_LasAqimVECCUM2iVY0YKZbnzKIfaDEwrpZbAWuG0bRs9TPXSiNpw13YKkWvBxZhML7EBEbenFI42_WyvH4l_cRVddQ</addsrcrecordid><sourcetype>Publisher</sourcetype><iscdi>true</iscdi><recordtype>conference_proceeding</recordtype></control><display><type>conference_proceeding</type><title>Differential method for undisturbed detection of 17β-estradiol using an integrated aptameric graphene nanosensor</title><source>IEEE Xplore All Conference Series</source><creator>Li, Yijun ; Zhu, Yibo ; Hao, Zhuang ; Wang, Cheng ; Zhang, Zhixing ; He, Miao ; Lin, Qiao</creator><creatorcontrib>Li, Yijun ; Zhu, Yibo ; Hao, Zhuang ; Wang, Cheng ; Zhang, Zhixing ; He, Miao ; Lin, Qiao</creatorcontrib><description>This paper presents a differential method based on the graphene field effect biosensor for the rapid and specific quantification of environmental pollution-related biochemical analyte. Selectively functionalizing one of the two identical graphene channels and calibrating the sensitivity difference of the two channels allowed us to extract analyte binding-induced signals by subtracting irregular and unpredictable background. Using this method we demonstrated real-time monitoring of 17β-estradiol in electrolytes with varying pH value. This work represents important progress of graphene field effect sensors toward use with complex real samples.</description><identifier>EISSN: 2160-1968</identifier><identifier>EISBN: 9781538647820</identifier><identifier>EISBN: 1538647826</identifier><identifier>DOI: 10.1109/MEMSYS.2018.8346543</identifier><language>eng</language><publisher>IEEE</publisher><subject>Biosensors ; Field effect transistors ; Graphene ; Microfluidics ; Sensitivity ; Testing ; Transconductance</subject><ispartof>2018 IEEE Micro Electro Mechanical Systems (MEMS), 2018, p.293-296</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/8346543$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>309,310,780,784,789,790,27925,54555,54932</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/8346543$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc></links><search><creatorcontrib>Li, Yijun</creatorcontrib><creatorcontrib>Zhu, Yibo</creatorcontrib><creatorcontrib>Hao, Zhuang</creatorcontrib><creatorcontrib>Wang, Cheng</creatorcontrib><creatorcontrib>Zhang, Zhixing</creatorcontrib><creatorcontrib>He, Miao</creatorcontrib><creatorcontrib>Lin, Qiao</creatorcontrib><title>Differential method for undisturbed detection of 17β-estradiol using an integrated aptameric graphene nanosensor</title><title>2018 IEEE Micro Electro Mechanical Systems (MEMS)</title><addtitle>MEMSYS</addtitle><description>This paper presents a differential method based on the graphene field effect biosensor for the rapid and specific quantification of environmental pollution-related biochemical analyte. Selectively functionalizing one of the two identical graphene channels and calibrating the sensitivity difference of the two channels allowed us to extract analyte binding-induced signals by subtracting irregular and unpredictable background. Using this method we demonstrated real-time monitoring of 17β-estradiol in electrolytes with varying pH value. This work represents important progress of graphene field effect sensors toward use with complex real samples.</description><subject>Biosensors</subject><subject>Field effect transistors</subject><subject>Graphene</subject><subject>Microfluidics</subject><subject>Sensitivity</subject><subject>Testing</subject><subject>Transconductance</subject><issn>2160-1968</issn><isbn>9781538647820</isbn><isbn>1538647826</isbn><fulltext>true</fulltext><rsrctype>conference_proceeding</rsrctype><creationdate>2018</creationdate><recordtype>conference_proceeding</recordtype><sourceid>6IE</sourceid><recordid>eNotUM1qAjEYTAuFivUJvOQF1uZLdvNzLNb-gNKDXnqSbPKtpmjWJvHQ1-qD9Jm6oHMZGIZhZgiZApsBMPO4WqzWn-sZZ6BnWtSyqcUNmRiloRFa1kpzdktGHCSrwEh9TyY5f7EBpubAYUS-n0PXYcJYgj3QI5Z972nXJ3qOPuRyTi166rGgK6GPtO8oqL_fCnNJ1of-QM85xB21kYZYcJdsGfz2VOwRU3B0EE57jEijjX3GmPv0QO46e8g4ufKYbF4Wm_lbtfx4fZ8_LasAqimVECCUM2iVY0YKZbnzKIfaDEwrpZbAWuG0bRs9TPXSiNpw13YKkWvBxZhML7EBEbenFI42_WyvH4l_cRVddQ</recordid><startdate>201801</startdate><enddate>201801</enddate><creator>Li, Yijun</creator><creator>Zhu, Yibo</creator><creator>Hao, Zhuang</creator><creator>Wang, Cheng</creator><creator>Zhang, Zhixing</creator><creator>He, Miao</creator><creator>Lin, Qiao</creator><general>IEEE</general><scope>6IE</scope><scope>6IH</scope><scope>CBEJK</scope><scope>RIE</scope><scope>RIO</scope></search><sort><creationdate>201801</creationdate><title>Differential method for undisturbed detection of 17β-estradiol using an integrated aptameric graphene nanosensor</title><author>Li, Yijun ; Zhu, Yibo ; Hao, Zhuang ; Wang, Cheng ; Zhang, Zhixing ; He, Miao ; Lin, Qiao</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i175t-33137c9ea7c09637a2cde6942019b668610b3c8ab58538d693492cbf7ee28323</frbrgroupid><rsrctype>conference_proceedings</rsrctype><prefilter>conference_proceedings</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Biosensors</topic><topic>Field effect transistors</topic><topic>Graphene</topic><topic>Microfluidics</topic><topic>Sensitivity</topic><topic>Testing</topic><topic>Transconductance</topic><toplevel>online_resources</toplevel><creatorcontrib>Li, Yijun</creatorcontrib><creatorcontrib>Zhu, Yibo</creatorcontrib><creatorcontrib>Hao, Zhuang</creatorcontrib><creatorcontrib>Wang, Cheng</creatorcontrib><creatorcontrib>Zhang, Zhixing</creatorcontrib><creatorcontrib>He, Miao</creatorcontrib><creatorcontrib>Lin, Qiao</creatorcontrib><collection>IEEE Electronic Library (IEL) Conference Proceedings</collection><collection>IEEE Proceedings Order Plan (POP) 1998-present by volume</collection><collection>IEEE Xplore All Conference Proceedings</collection><collection>IEEE Electronic Library (IEL)</collection><collection>IEEE Proceedings Order Plans (POP) 1998-present</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Li, Yijun</au><au>Zhu, Yibo</au><au>Hao, Zhuang</au><au>Wang, Cheng</au><au>Zhang, Zhixing</au><au>He, Miao</au><au>Lin, Qiao</au><format>book</format><genre>proceeding</genre><ristype>CONF</ristype><atitle>Differential method for undisturbed detection of 17β-estradiol using an integrated aptameric graphene nanosensor</atitle><btitle>2018 IEEE Micro Electro Mechanical Systems (MEMS)</btitle><stitle>MEMSYS</stitle><date>2018-01</date><risdate>2018</risdate><spage>293</spage><epage>296</epage><pages>293-296</pages><eissn>2160-1968</eissn><eisbn>9781538647820</eisbn><eisbn>1538647826</eisbn><abstract>This paper presents a differential method based on the graphene field effect biosensor for the rapid and specific quantification of environmental pollution-related biochemical analyte. Selectively functionalizing one of the two identical graphene channels and calibrating the sensitivity difference of the two channels allowed us to extract analyte binding-induced signals by subtracting irregular and unpredictable background. Using this method we demonstrated real-time monitoring of 17β-estradiol in electrolytes with varying pH value. This work represents important progress of graphene field effect sensors toward use with complex real samples.</abstract><pub>IEEE</pub><doi>10.1109/MEMSYS.2018.8346543</doi><tpages>4</tpages></addata></record>
fulltext fulltext_linktorsrc
identifier EISSN: 2160-1968
ispartof 2018 IEEE Micro Electro Mechanical Systems (MEMS), 2018, p.293-296
issn 2160-1968
language eng
recordid cdi_ieee_primary_8346543
source IEEE Xplore All Conference Series
subjects Biosensors
Field effect transistors
Graphene
Microfluidics
Sensitivity
Testing
Transconductance
title Differential method for undisturbed detection of 17β-estradiol using an integrated aptameric graphene nanosensor
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T04%3A23%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-ieee_CHZPO&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=proceeding&rft.atitle=Differential%20method%20for%20undisturbed%20detection%20of%2017%CE%B2-estradiol%20using%20an%20integrated%20aptameric%20graphene%20nanosensor&rft.btitle=2018%20IEEE%20Micro%20Electro%20Mechanical%20Systems%20(MEMS)&rft.au=Li,%20Yijun&rft.date=2018-01&rft.spage=293&rft.epage=296&rft.pages=293-296&rft.eissn=2160-1968&rft_id=info:doi/10.1109/MEMSYS.2018.8346543&rft.eisbn=9781538647820&rft.eisbn_list=1538647826&rft_dat=%3Cieee_CHZPO%3E8346543%3C/ieee_CHZPO%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-i175t-33137c9ea7c09637a2cde6942019b668610b3c8ab58538d693492cbf7ee28323%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rft_ieee_id=8346543&rfr_iscdi=true