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Ultrasound Tracking of the Acoustically Actuated Microswimmer

Objective: The purpose of this paper is to demonstrate the ultrasound tracking strategy for the acoustically actuated bubble-based microswimmer. Methods: The ultrasound tracking performance is evaluated by comparing the tracking results with the camera tracking. A benchtop experiment is conducted to...

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Bibliographic Details
Published in:IEEE transactions on biomedical engineering 2019-11, Vol.66 (11), p.3231-3237
Main Authors: Chen, Qiyang, Liu, Fang-Wei, Xiao, Zunding, Sharma, Nitin, Cho, Sung Kwon, Kim, Kang
Format: Article
Language:English
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Summary:Objective: The purpose of this paper is to demonstrate the ultrasound tracking strategy for the acoustically actuated bubble-based microswimmer. Methods: The ultrasound tracking performance is evaluated by comparing the tracking results with the camera tracking. A benchtop experiment is conducted to capture the motion of two types of microswimmers by synchronized ultrasound and camera systems. A laboratory developed tracking algorithm is utilized to estimate the trajectory for both tracking methods. Results: The trajectory reconstructed from ultrasound tracking method compares well with the conventional camera tracking, exhibiting a high accuracy and robustness for three different types of moving trajectories. Conclusion: Ultrasound tracking is an accurate and reliable approach to track the motion of the acoustically actuated microswimmers. Significance: Ultrasound imaging is a promising candidate for noninvasively tracking the motion of microswimmers inside the body in biomedical applications and may further promote the real-time control strategy for the microswimmers.
ISSN:0018-9294
1558-2531
DOI:10.1109/TBME.2019.2902523