Love wave biosensor to diagnose modification of cell viscoelasticy

In this work we present the development of an integrated microfluidic platform addressing several challenges. The sensor array combines a dual Rayleigh wave and Love wave for the diagnosis of the modification of cell viscoelasticity. Based on simulations taking into equations of motion and Navier-St...

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Bibliographic Details
Main Authors: Sarry, F., Chavez, P.A. Segura, Bonhomme, J., Olive, L., Beyssen, D., Oudich, M., Charette, P.G.
Format: Conference Proceeding
Language:English
Subjects:
biosensor
cell
Love wave
simulation
viscoelasticity
Online Access:Request full text
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Summary:In this work we present the development of an integrated microfluidic platform addressing several challenges. The sensor array combines a dual Rayleigh wave and Love wave for the diagnosis of the modification of cell viscoelasticity. Based on simulations taking into equations of motion and Navier-Stokes equation for the viscous liquid region, we evaluate and correlate the Love surface acoustic wave sensing part in order to enhance the sensitivity. The results corroborate the idea that the whole measurement system must be considered to develop an integrated optimized analysis system.
ISSN:2168-9229
DOI:10.1109/SENSORS43011.2019.8956914